Kisspeptin and LH pulsatile temporal coupling in PCOS patients

ConclusionsThe study of the endogenous kisspeptin and LH pulsatile release revealed the temporal coupling of kisspeptin with LH secretory pulses only in eumenorrheic. This data supports the hypothesis that neuroendocrine impairments in PCOS affect the coupling of kisspeptin with LH pulses and potentially worsen as the disease progresses, becoming unequivocally evident in oligomenorrheic PCOS patients.

http://link.springer.com/10.1007/s12020-018-1609-1

Source: Endocrine - May 4, 2018 Category: Endocrinology Source Type: research