MiRNA-17 encoded by the miR-17-92 cluster increases the potential for steatosis in hepatoma cells by targeting CYP7A1.

Conclusions: miR-17 is a novel regulator of CYP7A1 signaling in hepatic lipid metabolism, suggesting a potential therapeutic approach for fatty liver. PMID: 29721023 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/29721023?dopt=Abstract

Source: Cellular and Molecular Biology Letters - May 5, 2018 Category: Biochemistry Authors: Gong R, Lv X, Liu F Tags: Cell Mol Biol Lett Source Type: research