Postural orthostatic tachycardia syndrome and the potential role of mast cell activation

Though a sizeable amount of data connects mast cell activity to the neurologic system, less is known about the true clinical implications of this relationship. Even less is understood about treatment strategies in those with both allergic and neurologic complaints. This is particularly true in postural orthostatic tachycardia syndrome (POTS), a common type of dysautonomia, where patients are burdened by symptoms of orthostatic cerebral hypoperfusion and several other comorbidities that are likely influenced by autonomic tone.
Source: Autonomic Neuroscience: Basic and Clinical - Category: Neuroscience Authors: Tags: Review Source Type: research