Lively Debate Over Cesarean Risk After Induction of Labor Lively Debate Over Cesarean Risk After Induction of Labor

New evidence from the ARRIVE study calls into question the common wisdom that induction of labor increases the risk for cesarean delivery, and will lead to challenging conversations among providers.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health News Source Type: news

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The rates of cesarean section (CS) are increasing worldwide leading to an increased risk for maternal and neonatal complications in the subsequent pregnancy and labor. Previous studies have demonstrated that s...
Source: BMC Pregnancy and Childbirth - Category: OBGYN Authors: Tags: Research article Source Type: research
ConclusionsOverall, the BORN and CIHI-DAD databases had concordance on key birth and maternal data elements; however, additional work is needed to understand discrepancies identified.
Source: Archives of Gynecology and Obstetrics - Category: OBGYN Source Type: research
This study was designed to test the hypothesis that induced maternal noninfectious fever alters neonatal neural progenitor cell proliferation and enhances microglial activation in the rat dentate gyrus of the hippocampus. METHODS: Systemic vehicle or IL-6 was given 3 times to near-term pregnant rats (n = 7/group) every 90 minutes, and maternal core temperature was recorded. Neonatal brains were processed and analyzed for dentate gyrus cell proliferation (using Ki-67, n = 10/group, and glial fibrillary acidic protein, n = 6/group) and resident microglia activation (using ionized calcium-binding adaptor protein-1 [Iba-1...
Source: Anesthesia and Analgesia - Category: Anesthesiology Authors: Tags: Anesth Analg Source Type: research
ConclusionsIN-associated AEs were identified among patients with UC, with liver dysfunction often being reversible, while surgical resection was required in a high proportion of patients who developed intussusception. Both healthcare workers and patients should adequately recognize the potential for AEs with the use of IN.
Source: Journal of Gastroenterology - Category: Gastroenterology Source Type: research
ConclusionsChildren born early term are at increased risk of cognitive deficits, poorer school performance, and behavioral problems compared to children born full term.This article is protected by copyright. All rights reserved.
Source: Acta Obstetricia et Gynecologica Scandinavica - Category: OBGYN Authors: Tags: Systematic review Source Type: research
Publication date: Available online 9 May 2019Source: Pharmacological ResearchAuthor(s): Shajila Siricilla, Kelsi M. Knapp, Jackson H. Rogers, Courtney Berger, Elaine L. Shelton, Dehui Mi, Paige Vinson, Jennifer Condon, Bibhash C. Paria, Jeff Reese, Quanhu Sheng, Jennifer L. HeringtonAbstractNovel therapeutic regulators of uterine contractility are needed to manage preterm labor, induce labor and control postpartum hemorrhage. Therefore, we previously developed a high-throughput assay for large-scale screening of small molecular compounds to regulate calcium-mobilization in primary mouse uterine myometrial cells. The goal o...
Source: Pharmacological Research - Category: Drugs & Pharmacology Source Type: research
Despite women's preference for induction of labor (IOL) or dilation and evacuation (D&E) for pregnancy termination in the setting of second trimester fetal or pregnancy abnormality, many women are not given a choice between delivery methods. We investigated patient and clinical related factors associated with selecting IOL or D&E.
Source: Womens Health Issues - Category: Primary Care Authors: Tags: Original article Source Type: research
dsDNA breaks (DSBs) are resected in a 5′→3′ direction, generating single-stranded DNA (ssDNA). This promotes DNA repair by homologous recombination and also assembly of signaling complexes that activate the DNA damage checkpoint effector kinase Chk1. In fission yeast (Schizosaccharomyces pombe), genetic screens have previously uncovered a family of three xeroderma pigmentosum G (XPG)–related nucleases (XRNs), known as Ast1, Exo1, and Rad2. Collectively, these XRNs are recruited to a euchromatic DSB and are required for ssDNA production and end resection across the genome. Here, we studied why there a...
Source: Journal of Biological Chemistry - Category: Chemistry Authors: Tags: DNA and Chromosomes Source Type: research
Condition:   Induction of Labor Affected Fetus / Newborn Intervention:   Diagnostic Test: Transvaginal sonography Sponsor:   Rambam Health Care Campus Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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