Association of VDR gene polymorphisms and 22  bp deletions in the promoter region of TLR2Δ22 (‐196‐174) with increased risk of pulmonary tuberculosis: A case‐control study in tea garden communities of Assam

Journal of Clinical Laboratory Analysis, EarlyView.
Source: Journal of Clinical Laboratory Analysis - Category: Laboratory Medicine Authors: Source Type: research

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Authors: Villena-Suarez JR, Vicente W, Taxa L, Cuéllar L, Nuñez-Butrón MT, Villegas V, Castillo M, Castañeda CA Abstract Tuberculosis (TB) is a major public health problem that, due to the clinical variability of its presentation, can be confused with cancer. The aim of this study was to identify the clinical-radiological characteristics and to describe the methodology that allowed to achieve a TB diagnosis in patients referred to the National Institute of Neoplastic Diseases (INEN) with a presumed diagnosis of cancer between 2014 and 2016. The study included 170 patients (52.4% men) wit...
Source: Revista Peruana de Medicina de Experimental y Salud Publica - Category: International Medicine & Public Health Tags: Rev Peru Med Exp Salud Publica Source Type: research
Authors: Cortez-Bazán N, Delgado JR, Galdos O, Huicho L Abstract Pott's disease is a health problem in developing countries and its diagnosis in children is a challenge. Here we present the case of a two-year-old boy with Pott's disease involving T1 to T3 thoracic vertebrae. The clinical presentation was characterized by difficulty walking, fever, cough, and dyspnea. At physical examination, kyphosis and bony prominence were observed in the cervicodorsal area. A positive tuberculin test was obtained, and Mycobacterium tuberculosis was isolated via culture of the gastric aspiration sample. The spine MRI showe...
Source: Revista Peruana de Medicina de Experimental y Salud Publica - Category: International Medicine & Public Health Tags: Rev Peru Med Exp Salud Publica Source Type: research
Authors: Cegielski JP Abstract Multidrug-resistant (MDR) tuberculosis (TB) emerged shortly after introduction of rifamycins in the 1960s; isoniazid resistance had already emerged by the mid-1950s. Without these two drugs, tuberculosis is very difficult and costly to treat, with unacceptably high rates of treatment failure, death, loss to follow-up, and no known preventive treatment. Global attention first focused on MDR TB in the early 1990s when nosocomial outbreaks with high case fatality rates were reported in many countries. Prevalence data for MDR TB on a global scale first became available in 1997. In 2016, a...
Source: Revista Peruana de Medicina de Experimental y Salud Publica - Category: International Medicine & Public Health Tags: Rev Peru Med Exp Salud Publica Source Type: research
Could a vaccine for type-1 diabetes be on the horizon? In a new study, a small group of people with type 1 diabetes who were given a vaccine showed improvement in their blood sugar levels to nearly normal levels—and the changes lasted for five to eight years. The study, published Thursday in the journal npj Vaccines by researchers at Massachusetts General Hospital, looked at nine people with type 1 diabetes who were given a vaccine to prevent tuberculosis, called bacillus Calmette-Guérin (BCG). They had two injections, four weeks apart. Levels of their hemoglobin a1c (HbA1c), which measures a person’s bl...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized diabetes healthytime Source Type: news
A cheap, generic tuberculosis vaccine lowered blood glucose levels in nine patients with Type I diabetes and the effects lasted for years, according to a study published this week in npj Vaccines. The study was conducted at Massachusetts General Hospital by Dr. Denise Faustman – a name that has long been saddled with controversy in the diabetes community, due in large part to a dispute with the JDRF after the organization declined to fund her work. Get the full story at our sister site, Drug Delivery Business News. The post Generic drug shows promise as diabetes vaccine in small, years-long s...
Source: Mass Device - Category: Medical Devices Authors: Tags: Diabetes Pharmaceuticals Research & Development Massachusetts General Hospital Source Type: news
A little more than three years after getting two tuberculosis shots four weeks apart, about 50 people with type 1 diabetes saw their long-term average blood sugar levels drop significantly -- and for at least five years.
Source: WebMD Health - Category: Consumer Health News Source Type: news
BOSTON (CBS) – Researchers at Mass General Hospital announced a breakthrough in treating Type 1 Diabetes. In a long-term study released Thursday, patients in a clinical trial had their blood sugar levels restored to near normal, with lasting results. Patients in the trial received two doses of the bacillus Calmette-Guerin (BCG) vaccine, an inexpensive vaccine that is widely used to prevent tuberculosis. Results were not immediate, but after three years, every patient, “showed an improvement in HbA1c to near normal levels – improvement that persisted for the following five years,” MGH said in a news ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Boston News Health Syndicated Local Diabetes Mass General Hospital Source Type: news
Research at Massachusetts General Hospital looks increasing like a long-term cure for type 1 diabetes, with a newly released study on Thursday showing patients have normal blood sugar levels eight years after a clinical trial. In research published Thursday in journal npj Vaccines, patients who had been treated with the bacillus Calmette-Guerin (BCG) vaccine — an inexpensive, generic vaccine used around the world to prevent tuberculosis — had normal blood sugar levels eight years after the…
Source: bizjournals.com Health Care:Physician Practices headlines - Category: American Health Authors: Source Type: news
Research at Massachusetts General Hospital looks increasingly like a long-term cure for type 1 diabetes, with a newly released study showing patients have normal blood sugar levels eight years after a clinical trial. In research published Thursday in journal npj Vaccines, patients who had been treated with the bacillus Calmette-Guerin (BCG) vaccine — an inexpensive, generic vaccine used around the world to prevent tuberculosis — had normal blood sugar levels eight years after the trial ended.…
Source: bizjournals.com Health Care:Physician Practices headlines - Category: American Health Authors: Source Type: news
Research at Massachusetts General Hospital looks increasing like a long-term cure for type 1 diabetes, with a newly released study on Thursday showing patients have normal blood sugar levels eight years after a clinical trial. In research published Thursday in journal npj Vaccines, patients who had been treated with the bacillus Calmette-Guerin (BCG) vaccine — an inexpensive, generic vaccine used around the world to prevent tuberculosis — had normal blood sugar levels eight years after the…
Source: bizjournals.com Health Care News Headlines - Category: Health Management Authors: Source Type: news
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