Association of VDR gene polymorphisms and 22  bp deletions in the promoter region of TLR2Δ22 (‐196‐174) with increased risk of pulmonary tuberculosis: A case‐control study in tea garden communities of Assam

Journal of Clinical Laboratory Analysis, EarlyView.
Source: Journal of Clinical Laboratory Analysis - Category: Laboratory Medicine Authors: Source Type: research

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Publication date: Available online 7 December 2018Source: Journal of Pediatric Surgery Case ReportsAuthor(s): Adjoba Manuela Ehua, Martial Olivier Moulot, Josaphat Konvolbo, Kouame Soroboua Agbara, Idalia Taguela Ajoumissi, Jean Marie Konan, Ibrahim Traoré, Landry Konan, Stéphane Sable, Roumanatou Bankole
Source: Journal of Pediatric Surgery Case Reports - Category: Surgery Source Type: research
ConclusionAllicin/garlic extract alone or as an adjunct to classical antibiotics holds great promise for treatment of drug-sensitive as well as drug-resistant TB. These results warrant further study and validation of allicin for treatment of TB.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
We report a case of Primary Tuberculous Otitis Media who presented with Bezold ’s Abscess. Patient underwent Mastoidectomy. Diagnosis was made with the Histopathological examination of the suspicious extensive pale granulation tissue. Patient was started on ATT immediately. Greater awareness regarding the disease is needed to make an early diagnosis. Late diagnosis increases the risk of complications. Anti Tubercular Therapy is the treatment of choice. Surgical intervention may be added to drug therapy. In cases with complications, radical surgery will be needed. Bezold’s abscess is a rare complication of Otiti...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - Category: ENT & OMF Source Type: research
Authors: McIlleron H, Chirehwa MT Abstract INTRODUCTION: Drug concentrations in tuberculosis patients on standard regimens vary widely with clinically important consequences. Areas covered: We review the available literature identifying factors correlated with pharmacokinetic variability of antituberculosis drugs. Based on population pharmacokinetic models and the weight, height and sex distributions in a large data base of African tuberculosis patients, we propose simplified weight-based doses of the available fixed dose combination(FDC) for adults with drug susceptible tuberculosis. Emerging studies will support ...
Source: Expert Review of Anti-Infective Therapy - Category: Infectious Diseases Tags: Expert Rev Anti Infect Ther Source Type: research
With the help of PET scans, researchers at Johns Hopkins Medicine are gathering...Read more on AuntMinnie.comRelated Reading: Cardiac PET helps assess revascularization benefits PET/CT key to NIH's tuberculosis research plan PET technique could aid diabetic therapy monitoring Novel PET tracer shows promise for neuroendocrine tumors Can AI accurately diagnose tuberculosis from chest x-rays?
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
We present a rare case of TB orchitis in a 6-month old male infant who presented with a painless, firm left testicular mass that was initially managed as a testicular tumor but later confirmed to be TB orchitis after histological analysis. The aim of this report is to highlight the similarity of presentation between testicular TB and testicular tumors in children which may only be differentiated histologically therefore creating a diagnostic enigma.
Source: Journal of Pediatric Surgery Case Reports - Category: Surgery Source Type: research
Condition:   Tuberculosis Intervention:   Diagnostic Test: Quantiferon Gold Plus Test Sponsors:   Biomedical Research Center EPLS;   Biofabri, S.L;   TuBerculosis Vaccine Initiative;   Universidad de Zaragoza;   University of Cape Town;   Institut Pasteur de Madagascar Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Publication date: Available online 6 December 2018Source: The Lancet HIVAuthor(s): Anna Turkova, Alasdair Bamford
Source: The Lancet HIV - Category: Infectious Diseases Source Type: research
This study is registered with ClinicalTrials.gov, number NCT02348177.FindingsBetween Jan 30, 2013, and Nov 9, 2015, 96 children with a median age of 18·2 months (IQR 9·6–26·8) were enrolled. Of these 96 children, 80 (83%) completed the first three pharmacokinetic evaluations. Tuberculosis therapy was started before antiretrovirals in 70 (73%) children. The model-predicted percentage of morning Cmin of less than 1·0 mg/L after tuberculosis treatment without super-boosting was 8·8% (95% CI 0·6–19·8) versus 7·6% (0·4–16·2) during super-boo...
Source: The Lancet HIV - Category: Infectious Diseases Source Type: research
The number of traffic-related deaths reached a high of 1.35 million in 2016, according to the 2018 Global Status Report on Road Safety, released by the World Health Organization on Friday. It has also moved up to the eighth leading cause of death for people of all ages, ahead of HIV/AIDS and tuberculosis.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news
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