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Sleep Duration Linked to Health-Related QoL in Kidney Disease

THURSDAY, May 3, 2018 -- Sleep duration is associated with health-related quality of life among patients with chronic kidney disease (CKD), according to a study published online May 3 in the Clinical Journal of the American Society of...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news

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End-stage renal disease chronic itch is a frequent symptom that bothers patients with advanced stages of chronic kidney disease. The pathogenesis of the chronic itch symptom is complex and not yet fully understood and includes many metabolic, immunologic, and neurogenic factors. A significant burden of the disease results in decreased quality of life with sleep impairment, depressive symptoms, and increased mortality of affected individuals. No treatment of choice is available; topical therapy (emollients), phototherapy (UV-B), and systemic therapy (antiepileptics, opioid agonists, and antagonists) provide significant reli...
Source: Dermatologic Clinics - Category: Dermatology Authors: Source Type: research
The impact of a nondipping blood pressure (BP) pattern, defined as (awake systolic BP – sleep systolic BP)/awake systolic BP 
Source: The Journal of Clinical Hypertension - Category: Cardiology Authors: Tags: ORIGINAL PAPER Source Type: research
Abstract Resistant hypertension is defined as high blood pressure that remains uncontrolled despite treatment with at least three antihypertensive drugs at adequate doses. Resistant hypertension is an increasingly common clinical problem in older age, obesity, diabetes, sleep apnea, and chronic kidney disease. Although the direct vasodilator minoxidil was introduced in the early 1970s, only recently has this drug been shown to be particularly effective in a subgroup of patients with treatmentā€resistant or uncontrolled hypertension. This pharmacological approach is interesting from a mechanistic perspective as minoxidil i...
Source: Microcirculation - Category: Research Authors: Tags: INVITED REVIEW Source Type: research
The objective of this study is to describe aspects of health-related quality of life (HRQOL) in Mexican patients with antineutrophil cytoplasmic-associated vasculitis (AAV). Cross-sectional comparison study includes patients with established AAV and a comparison group with rheumatoid arthritis (RA), chronic kidney disease (CKD), and healthy subjects. Variables considered were: socio-demographic data, comorbidities, laboratory, disease activity, damage, and Physician ’s and Patient’s Global Assessment (PhGA and PtGA). The following measurements were done: Pittsburg sleep quality index, Multidimesional Fatigue In...
Source: Rheumatology International - Category: Rheumatology Source Type: research
The metabolic syndrome —otherwise called syndrome X, insulin resistance syndrome, Reaven syndrome, and “the deadly quartet”—is the name given to the aggregate of clinical conditions comprising central and abdominal obesity, systemic hypertension, insulin resistance (or type 2 diabetes mellitus), and atherogenic dy slipidemia. It is a prothrombotic and proinflammatory state characterized by increased inflammatory cytokine activity. In addition to inflammatory dermatoses such as psoriasis, lichen planus, and hidradenitis suppurativa, metabolic syndrome is also commonly associated with accelerated athe...
Source: Clinics in Dermatology - Category: Dermatology Authors: Source Type: research
This study by Wegman and co-authors provides evidence for how further actions should be taken.byBroberg K. doi:10.5271/sjweh.3698
Source: Scandinavian Journal of Work, Environment and Health - Category: Occupational Health Tags: Editorial Source Type: research
Conclusions: In CKD patients impaired sleep quality increases BPV, might contribute to their disease progression and worsen prognosis. Searching for sleep problems in CKD patients could help planning their treatment of sleep problems contributing to CV risk reduction. Our data provide the rationale working hypothesis for the need of studies with larger number of patients aimed to demonstrate improved outcome of CKD progression and CV risk with the treatment also of sleep disorders.Kidney Blood Press Res 2017;42:804 –815
Source: Kidney and Blood Pressure Research - Category: Urology & Nephrology Source Type: research
Purpose: With sleep apnoea syndrome (SAS) being a factor for cardiovascular morbidity and mortality, we hypothesized that severity of SAS is reflected by elevated high-sensitive troponin T (hsTnT).Methods: Retrospective analysis of 563 consecutive sleep apnoea patients with regard to hsTnT, sleep and overnight respiratory parameters, CRP, Creatinine/GFR, NTproBNP as well as pulmonary function test.Results: Of 563 patients, 415 had positive hsTnT (≥14pg/ml). No association with severity of sleep apnoea syndrome as defined by apnoea-hypopnoea-index (AHI), oxygen desaturation index (ODI) or lowest saturation during the nig...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Sleep and Control of Breathing Source Type: research
Background: Previous studies demonstrated a direct causal effect of chronic kidney disease on both obstructive and central sleep apnoea. On the other hand, kidneys are sensitive to hypoxia and they might be affected by intermittent desaturation caused by sleep apnoea. Here we test the hypothesis that continuous positive airways pressure therapy (CPAP), which prevents these episodes of desaturation, could have a protective role in the kidney function of patients with obstructive sleep apnoea (OSA).Methods: Renal function measurements (U&E) of patients with OSA, who were initiated on CPAP were retrospectively collected. We e...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Sleep and Control of Breathing Source Type: research
The objective is to study this association in the Chilean adult population.Material and method: From the National Health Survey 2010 the risk level of OSA was obtained in subjects ≥18 years, using a clinical prediction rule (RPC) based on the STOP-Bang Questionnaire. With the total score the subjects were classified as Low (
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Epidemiology Source Type: research
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