Treatment of vulvar mycosis fungoides tumors with localized radiotherapy

Primary cutaneous lymphomas are a heterogeneous group of lymphoid malignancies and are the second most common group of extranodal non-Hodgkin lymphoma (NHL) following gastrointestinal lymphomas.1 NHL involving the female genitalia is unusual, posing diagnostic and therapeutic challenges.2-4 Rare cases of vulvar NHL presenting as a vulvar mass were mostly diagnosed as diffuse large B-cell lymphoma and had an aggressive course.3,5 Cases of cutaneous T-cell lymphoma (CTCL) involving the vulva have been rarely reported.
Source: Clinical Lymphoma, Myeloma and Leukemia - Category: Hematology Authors: Tags: Case Report Source Type: research

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Publication date: Available online 12 December 2019Source: Respiratory Medicine Case ReportsAuthor(s): Itthiphat Arunsurat, Wipa Reechaipichitkul, Apichart So-Ngern, Piti Ungareevittaya, Nipon Chaisuriya, Nattiya Teawtrakul, Pailin Ratanawatkul, Worawat ChumpangernAbstractMultiple myeloma (MM) is a hematologic malignancy of plasma cell origin. Incidence of pleural effusion in multiple myeloma patients is approximately 6%. Myelomatous pleural effusions (MPE) are rare and occur in less than 1% of all MM cases. MPE is associated with advanced diseases, decreased survival time, and poor treatment response.In our case report, w...
Source: Respiratory Medicine Case Reports - Category: Respiratory Medicine Source Type: research
We present a case of ovarian lymphoma, in which an ambiguous intraoperative pathologic report led to overtreatment (unnecessary surgery). A 73-yr-old woman with fatigue and low-grade fever was diagnosed as having a left ovarian tumor by imaging modalities. Exploratory laparotomy was carried out to confirm the diagnosis. The frozen tissue sections of the ovarian tumor showed condensed proliferation of atypical round cells accompanied with a few small lymphocytes. The pathologists could not determine whether this tumor was a lymphoma or another malignancy (eg, dysgerminoma). Hence, they reported it to gynecologists who opera...
Source: International Journal of Gynecological Pathology - Category: Pathology Tags: PATHOLOGY OF THE UPPER TRACT: CASE REPORTS Source Type: research
Risk for postrelapse mortality 2.7 - , 3.5 - fold higher for Hispanics, non - Hispanic blacks versus whites
Source: The Doctors Lounge - Oncology - Category: Cancer & Oncology Tags: Oncology, Pediatrics, Pharmacy, Journal, Source Type: news
Publication date: Available online 11 December 2019Source: The Lancet HaematologyAuthor(s): Xavier Thomas
Source: The Lancet Haematology - Category: Hematology Source Type: research
This study is registered with Clinicaltrials.gov, number NCT02560025, and has completed enrolment.FindingsBetween Dec 31, 2015, and Aug 1, 2017, we enrolled a total of 39 eligible patients. 19 (49%) of 39 patients had secondary acute myeloid leukaemia and three (8%) had therapy-related acute myeloid leukaemia. At mid-induction, 33 (85%) of 39 patients showed marrow aplasia, six (15%) received re-induction. The median follow-up was 13·7 months (IQR 12·7–14·4). Composite remission was 64% (two-stage 95% CI 48–79), with 20 (51%) of 39 patients achieving complete remission and five (13%) achiev...
Source: The Lancet Haematology - Category: Hematology Source Type: research
Condition:   Multiple Myeloma Interventions:   Biological: bb2121 carfilzomib;   Drug: Fludarabine;   Drug: Cyclophosphamide;   Drug: Lenalidomide Sponsor:   Celgene Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Acute Lymphoblastic Leukemia ,Lymphomas Intervention:   Biological: Anti-CD19 CAR-T Sponsor:   The First Affiliated Hospital of Nanchang University Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Myeloid Neoplasm;   Recurrent Acute Myeloid Leukemia;   Refractory Acute Myeloid Leukemia Interventions:   Drug: Cladribine;   Drug: Cytarabine;   Biological: Granulocyte Colony-Stimulating Factor;   Drug: Mitoxantrone Sponsors:   University of Washington;   National Cancer Institute (NCI) Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Acute Myeloid Leukemia;   Myeloid Neoplasm Interventions:   Drug: Liposome-encapsulated Daunorubicin-Cytarabine;   Drug: Cladribine;   Drug: Cytarabine;   Biological: Granulocyte Colony-Stimulating Factor;   Drug: Mitoxantrone;   Other: Questionnaire Administration;   Other: Quality-of-Life Assessment Sponsors:   Fred Hutchinson Cancer Research Center;   National Cancer Institute (NCI);   Jazz Pharmaceuticals Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Acute Leukemia;   Acute Lymphoblastic Leukemia;   Acute Myeloid Leukemia;   Adult Diffuse Large Cell Lymphoma;   Anaplastic Large Cell Lymphoma;   Burkitt Lymphoma;   Chronic Myelogenous Leukemia, BCR-ABL1 Positive;   Chronic Myelomonocytic Leukemia;   Hodgkin Lymphom a;   Lymphoblastic Lymphoma;   Lymphoplasmacytic Lymphoma;   Mantle Cell Lymphoma;   Mixed Phenotype Acute Leukemia;   Myelodysplastic Sy...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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