Haemoglobin A1c or Glycated Albumin for Diagnosis and Monitoring Diabetes: An African Perspective
AbstractDiabetes mellitus (DM) has reached epidemic proportions across the globe with the largest increases seen in sub-Saharan Africa. Those that are diagnosed are largely poorly controlled. This review summarizes the limitations of the use of glycated haemoglobin (HBA1c) in Africa and current knowledge on the utility of glycated albumin and fructosamine in African patients. The diagnosis and monitoring of DM in African patients may be compromised by associated conditions like sickle cell anaemia, chronic kidney disease and HIV infection. Glycated albumin reflects short term glycaemia and is not affected by many conditions that alter HbA1c. It can be measured enzymatically, and this review discusses methods for analysis, and discusses the advantages and limitations in specific situations with an emphasis on conditions that also affect HbA1c.
CONCLUSIONS: . Excess weight, abdominal obesity, and high cholesterol were the most prevalent risk factors in women. The metabolic syndrome component with the highest prevalence in community kitchen users in a district of Lima is abdominal obesity. PMID: 29924275 [PubMed - in process]
The Eversense is implanted under the skin in a short office procedure and worn for up to 90 days.FDA Approvals
The Afinion HbA1c Dx assay, for use with the Afinion AS100 Analyzer, is the first rapid point-of-care test cleared to diagnose diabetes and assess a patient's risk of developing the disease.FDA Approvals
Authors: Dayanand P, Sandhyavenu H, Dayanand S, Martinez J, Rangaswami J Abstract Vascular calcification is known to be a strong risk factor for cardiovascular adverse events and mortality. Atherosclerosis, diabetes, aging, abnormal bone mineral homeostasis and high uremic milieu such as chronic kidney disease are major factors that contribute to the progression of vascular calcification. Several mechanisms such as the osteoblastic transition of vascular smooth muscle cells in response to oxidative stress have shed light on the active nature of vascular calcification, which was once thought to be a passive process....
Companion Medical launched today Insights by InPen, a diabetes management system that aggregates and analyzes data from Companion’s connected insulin injection pen. The company’s Insights by InPen system provides users with their average glucose, average total daily insulin dose, dose calculator usage, missed doses and more, according to Companion Medical. Get the full story at our sister site, Drug Delivery Business News. The post Companion Medical launches data management system for smart insulin pen appeared first on MassDevice.
Could a vaccine for type-1 diabetes be on the horizon? In a new study, a small group of people with type 1 diabetes who were given a vaccine showed improvement in their blood sugar levels to nearly normal levels—and the changes lasted for five to eight years. The study, published Thursday in the journal npj Vaccines by researchers at Massachusetts General Hospital, looked at nine people with type 1 diabetes who were given a vaccine to prevent tuberculosis, called bacillus Calmette-Guérin (BCG). They had two injections, four weeks apart. Levels of their hemoglobin a1c (HbA1c), which measures a person’s bl...
Authors: Jongjirasiri S, Waeosak P, Laothamatas J, Sritara C, Saengruang-Orn S Abstract Objective: To determine effects of obesity and gender on left ventricular mass in normotensive and hypertensive Thai patients using 320-slice cardiac computed tomography (CT). Material and Method: Left ventricular mass (LVM) obtained from 320-slice coronary CT angiogram was compared in 597 normotensive subjects (175 men [65 obese] and 422 women [133 obese], aged 55±7 years) and 483 hypertensive patients (180 men [104 obese] and 303 women [170 obese], aged 60±7 years). Obesity in Asian population was defined by ...
Conclusion: Most PAD in diabetic patients was asymptomatic. The atherosclerotic risk factor control was poor in this group. PMID: 29916234 [PubMed - in process]
Conclusion: Applying developed PPH risk score is a practical way to identify patients who are at high-risk for developing PPH for an early detection, treatment, and transfer. PMID: 29911829 [PubMed - in process]
Conclusion: Personal and neighborhood supports are two potential leverage points for self-management support interventions for Thai patients with type 2 diabetes. Patients with low and high personal supports may need different strategies for neighborhood support. PMID: 29911793 [PubMed - in process]