Advance and Application of DNA-functionalized Nanoparticles.

Advance and Application of DNA-functionalized Nanoparticles.
Curr Med Chem. 2018 Apr 30;:
Authors: Zhang X, Wang F, Sheng JL, Sun MX
Abstract
DNA-functionalized nanoparticle (DfNP) technology, the integration of DNA with nanotechnology, has emerged over recent decades as a promising biofunctionalization tool in the light of biotechnological approaches. The development of DfNPs has exhibited significant potential for several biological and biomedical applications. In this review, we focus on the mechanism of a series of DNA-NP nanocomposites and highlight the superstructures of DNA-based NPs. We also summarize its applications of these nanocomposites in cell imaging, cancer therapy and bioanalytical detection.
PMID: 29714139 [PubMed - as supplied by publisher]

Source: Current Medicinal Chemistry - April 30, 2018 Category: Chemistry Authors: Zhang X, Wang F, Sheng JL, Sun MX Tags: Curr Med Chem Source Type: research