Oncology Acupuncture for Chronic Pain in Cancer Survivors

Chronic pain syndromes associated with cancer treatment are common but difficult to manage. The American Society of Clinical Oncology recently published a practice guideline to address the unmet needs of cancer survivors, Management of Chronic Pain in Survivors of Adult Cancers, which stresses the importance of implementing integrative therapies including acupuncture. This review focuses on randomized clinical trials of acupuncture for chronic pain in cancer survivors, including its use in chemotherapy-induced peripheral neuropathy, aromatase inhibitor-associated arthralgia, and post neck dissection pain, and provides future directions of oncology acupuncture research in cancer survivorship. The features of oncology acupuncture are also discussed.
Source: Hematology/Oncology Clinics of North America - Category: Cancer & Oncology Authors: Source Type: research

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Patients undergoing treatment for cancer commonly experience symptoms such as sleep disturbance, pain, anxiety, depression, and low energy/fatigue (SPADE), subsequently altering physical function and complicating effective symptom management. However, little is known about the frequency, severity, and clustering of SPADE symptoms in individuals with chronic painful chemotherapy-induced peripheral neuropathy (CIPN). The purpose of this cross-sectional, secondary analysis was to describe the frequency, severity, and clustering of SPADE symptoms and their association with physical function in individuals with chronic painful CIPN.
Source: Pain Management Nursing - Category: Nursing Authors: Tags: Original Article Source Type: research
Development of chronic pain associated with chemotherapy-induced peripheral neuropathy (CIPN) compromises the effectiveness of chemotherapies to treat cancers and greatly impacts thousands of lives. The causative mechanisms remain poorly understood. However, emerging evidence implicates unchecked neuroinflammation as a determinant factor in its development. We now demonstrate that the dysregulation of adenosine metabolism and loss of its signaling govern the extent of neuroinflammation in oxaliplatin-treated rodents.
Source: The Journal of Pain - Category: Materials Science Authors: Source Type: research
Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of cancer treatment, and may adversely affect quality of life for years.
Source: Journal of Pain and Symptom Management - Category: Palliative Care Authors: Source Type: research
Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of cancer treatment and may adversely affect quality of life (QOL) for years.
Source: Journal of Pain and Symptom Management - Category: Palliative Care Authors: Tags: Original Article Source Type: research
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Source: Journal of Biological Chemistry - Category: Chemistry Authors: Tags: Molecular Bases of Disease Source Type: research
ConclusionPeripheral neuropathy is a common complication in patients receiving platins and can be particularly painful. There is significant heterogeneity among studies regarding the method for diagnosing peripheral neuropathy. Nerve conduction studies are the gold standard and should be performed in patients receiving platins and complaining of neuropathic symptoms post-treatment.
Source: Pain and Therapy - Category: Anesthesiology Source Type: research
Conclusion.The preemptive use of pregabalin during OXA infusions was safe, but did not decrease the incidence of chronic pain related to OXAIPN.
Source: The Oncologist - Category: Cancer & Oncology Authors: Tags: Symptom Management and Supportive Care, Clinical Trial Results, Gastrointestinal Cancer Source Type: research
ConclusionsResults of this pilot study do not support the use of minocycline to prevent CIPN, but suggest that it may reduce P-APS and decrease fatigue; further study of the impact of this agent on those endpoints may be warranted.
Source: Supportive Care in Cancer - Category: Cancer & Oncology Source Type: research
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Source: Neurotherapeutics - Category: Neurology Source Type: research
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