Selecting an antidepressant

Hello, I am a soon to be Psychiatry PGY-1 resident. I am obviously still learning the fundamentals of psychiatry and want to pose a question to this forum. How do you go about selecting a particular antidepressant for a patient who is presenting with anxiety or depression? Some "textbook" cases seem obvious to me, like in an elderly person who is losing weight and has depressed mood, mirtazepine would be a good choice. Or a person with major depression who smokes, burpropion would be a good... Selecting an antidepressant
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