Sodium chloride exacerbates dextran sulfate sodium-induced colitis by tuning proinflammatory and antiinflammatory lamina propria mononuclear cells through p38/MAPK pathway in mice.

CONCLUSION: Proinflammatory macrophages may play an essential role in the onset and development of NaCl-promoted inflammation in DSS-induced colitis. The underlining mechanism involves up-regulation of the p38/MAPK axis. PMID: 29713131 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/29713131?dopt=Abstract

Source: World Journal of Gastroenterology : WJG - April 28, 2018 Category: Gastroenterology Authors: Guo HX, Ye N, Yan P, Qiu MY, Zhang J, Shen ZG, He HY, Tian ZQ, Li HL, Li JT Tags: World J Gastroenterol Source Type: research