Blogosphere, Here I Am

I'm finally back in the blogosphere. (I'm not sure I like that term but I'll use it). Blogging really helps me cope with life. Its where I share my emotions and thoughts and I've missed it. But I did need the hibernation.Since the middle of February, when my father stopped his chemo and was gone in two weeks, until now, I have been on a roller coaster of emotions. I have been lucky enough not to have lost a family member since my grandmother passed away in 1983 so this was very difficult. In addition, my health made it more difficult for me to do much to help the rest of my family pull together the memorial service, help clean out my parent's house (my father was a packrat in many ways), and spend more time with my mother. We have also had visiting relatives to deal with.Last week, we left town for a week to take a much needed break and went to a friend's daughter's wedding in the Midwest. The physical distance let me strengthen the break so I have returned mentally healthier but more exhausted from our travels.However I have a backlog of emotional issues to work through. Which is why I am back to blogging. This blog allows me to work through my emotions and cope with my decrepit body.I think my focus may switch from breast cancer for a bit but I'm back.
Source: Caroline's Breast Cancer Blog - Category: Cancer & Oncology Tags: blogging emotional toll stress Source Type: blogs

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We reported an isolated case and 1 family with several individuals affected by CS. The isolated case showed typical features including fibrocystic breast disease, benign thyroid nodules, and multiple papillomatous lesions in the face and oral cavity and was caused by a novel nonsense mutation (c.940 G>T) in the PTEN gene. In the family, the proband showed erythema nodosum, duodenal ulcer, intestinal polyps, cervical lipoma, renal cysts, and glaucoma, whereas her family revealed multiple members with intestinal polyps and a sister with breast cancer diagnosed at early age.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - Category: ENT & OMF Authors: Source Type: research
The 8 cases selected for this presentation include medication-related osteonecrosis of the jaw (MRONJ) treated conservatively: 2 cases of breast cancer metastasis, 3 cases of multiple myeloma, and 3 cases of osteoporosis. Two of them occurred in the implant area and in 1 case, the treatment was concluded with hyperbaric oxygen therapy. In 5 cases, a bisphosphonate was given via intravenous route and 3 cases by oral administration. Only 1 case had a combination of bisphosphonates and monoclonal antibody (denosumab).
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - Category: ENT & OMF Authors: Source Type: research
Diffuse large B-cell lymphomas (DLBCLs) are uncommon in the mouth; however, they are the commonest type of non-Hodgkin lymphomas at this site. Preferentially, they affect tonsils and their occurrence in the upper lip is rare. This work reports a case of DLBCL arising in the left upper lip of a 73-year-old white woman that was recently diagnosed as having advanced breast cancer besides being a carrier of Parkinson and Alzheimer diseases. The mucosal surface of the upper lip displayed a solitary, fast-growing, painful, ulcerated, reddish, and sessile 4-cm-sized swelling without cervical lymph node involvement at presentation.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - Category: ENT & OMF Authors: Source Type: research
The reported case is of a 57-year-old female patient with metastatic breast cancer in liver, pleura, and bones treated with eribulin without antiresorptives and sent for assessment of submandibular abscess after extraction of tooth 37 two months before. The examination showed increased volume in the buccal vestibule, retromolar trigone region, and left buccal mucosa without mucosal lesions, palpation hardening, or facial asymmetry. Tomography showed heterogeneous expansive lesion with peripheral enhancement and necrotic center in the left mandibular angle and branch (60  × 49 × 54 mm) with infiltration ...
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - Category: ENT & OMF Authors: Source Type: research
To evaluate the association of single nucleotide polymorphisms (SNPs) in the genes/loci IRF6, WNT3 A, GSK3 B, 8 q24, and WNT11, representing regions consistently altered in nonsyndromic oral clefts with breast and oral cancers in the Brazilian population.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - Category: ENT & OMF Authors: Source Type: research
ConclusionsOur data suggest H3K27me3 loss as an important event in CEMIP mediated breast cancer carcinogenesis and progression. Loss of H3K27me3 is specific for aggressive subtypes of breast cancer and may be a useful diagnostic marker.
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 14 December 2019Source: Social Science &MedicineAuthor(s): Catherine Bourgain, Lionel Pourtau, Chafika Mazouni, Martine Bungener, et Julia Bonastre
Source: Social Science and Medicine - Category: Psychiatry & Psychology Source Type: research
Authors: Kolarova I, Vanasek J, Odrazka K, Melichar B, Ryska A, Petera J, Vosmik M, Dolezel M Abstract Breast cancer with high expression of human epidermal growth factor receptor (HER)-2 represents a biologically and clinically heterogeneous group of neoplastic disorders. Importantly, hormone receptor expression has an effect on biological properties and affects the selection of therapies. On the basis of molecular genetics, four principal subtypes, including luminal A, luminal B, HER2-enriched (HER-2-E), and basal-like can be distinguished. Breast tumors characterized by HER-2 positivity and simultaneous expressi...
Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub - Category: Biomedical Science Tags: Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub Source Type: research
CONCLUSION: Available cervical and breast cancers screening services are not attuned to refugee women's views where this study focuses attention on the roles and practices of doctors in preventive health care for refugee women. Merging their perspectives with those of providers and policymaker's can fill the existing gaps and support to formulate the new interventions that will improve women's access to such preventative services. PMID: 31833117 [PubMed - as supplied by publisher]
Source: Health Promotion Journal of Australia - Category: International Medicine & Public Health Tags: Health Promot J Austr Source Type: research
Conclusion: MiR-7-5p suppresses NSCLC metastasis. Targeting miR-7-5p may contribute to the success of NSCLC therapy. PMID: 31832068 [PubMed - in process]
Source: Cellular and Molecular Biology Letters - Category: Biochemistry Authors: Tags: Cell Mol Biol Lett Source Type: research
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