Spatiotemporal Distribution of {beta}-Amyloid in Alzheimer Disease Is the Result of Heterogeneous Regional Carrying Capacities

Conclusion: The in vivo spatiotemporal distribution of Aβ in AD can be mathematically modeled using a logistic growth model in which the Aβ carrying capacity is heterogeneous across the brain but the exponential growth rate and time of half maximal Aβ concentration are constant.

Source: Journal of Nuclear Medicine - May 1, 2018 Category: Nuclear Medicine Authors: Whittington, A., Sharp, D. J., Gunn, R. N., for the Alzheimers Disease Neuroimaging Initiative Tags: Clinical Source Type: research