XXIV World Congress of Asthma
XXIV World Congress of AsthmaDate: Tuesday, May 1, 2018Year: 2018Location: Tokyo, JapanContent-type: current_conferences
Glucocorticoids are the most widely used agents in the treatment of allergic bronchopulmonary aspergillosis (ABPA), a disorder characterised by immunologic reactions mounted against Aspergillus fumigatus colonising the airways of patients with asthma and cystic fibrosis [1, 2]. Unfortunately, the use of glucocorticoids is associated with several adverse reactions . A novel treatment strategy in ABPA would be the use of antifungal triazoles as monotherapy. Recently, we have shown that itraconazole was effective as monotherapy in acute-stage ABPA . Whether voriconazole monotherapy is also efficacious in acute-stage ABPA remains unknown.
AbstractFungal spores in ambient particulate matter (PM) is one of the major constituents which can adversely affect human health. For the first time, an investigation was conducted for 1 year at a residential region in north-east India to study the seasonal variation of PM10-associated fungal spore concentration and their diversity. Using fine particulate sampler, samples were collected at 12 h intervals for 1 week of every month during July 2016–June 2017. Twelve-hour averaged PM10 concentration was 79.74 μg/m3 and 103.47 μg/m3 during day and night time, respectively. Fungal spore...
AbstractAirborne fungal spores are well documented to trigger respiratory allergy. The present study provides baseline information on the quantitative and qualitative aspects of aerospores for the first time in a typical urban area of Kolkata metropolis, India. An aeromonitoring was performed by Burkard volumetric 7-day sampler for two consecutive years (August 2012 –July 2014). Total concentration, seasonal variations and intradiurnal periodicities of fungal spores were estimated. Spearman’s rank correlation analysis was performed using various weather parameters. The prevalence of fungal spore allergy was inv...
Authors: Sehgal IS, Dhooria S, Behera D, Agarwal R Abstract Allergic bronchopulmonary aspergillosis (ABPA) is a pulmonary disorder that results from immune responses mounted against antigens of Aspergillus fumigatus, resulting in non-specific respiratory symptoms and structural lung damage. Classically defined in individuals suffering from bronchial asthma and cystic fibrosis, ABPA has recently been described in other lung diseases including COPD, pulmonary tuberculosis, idiopathic bronchiectasis and others. Herein, we report the first case of ABPA complicating Swyer-James-Macleod's syndrome that was successfully t...
Aspergillus fumigatus is a ubiquitous ascomycete mould that can cause a wide spectrum of clinical syndromes. The pathological effects of A. fumigatus depend largely on the interplay between the pathogen and host immune response ranging from asymptomatic colonisation to life-threatening infection. Invasive aspergillosis (IA), the most severe form of A. fumigatus infection, predominantly affects immunocompromised patients. In contrast, immune hyperactivity can lead to allergic bronchopulmonary aspergillosis (ABPA) and fungal sensitization in severe asthma (SAFS).
Allergy,Volume 0, Issue ja, -Not available-.