miR-223 promotes the doxorubicin resistance of colorectal cancer cells via regulating epithelial-mesenchymal transition by targeting FBXW7.

In conclusion, miR-223/FBXW7 axis regulates doxorubicin sensitivity through EMT in CRC, which may lead to the development of individualized treatment in clinical practice. PMID: 29701752 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29701752?dopt=Abstract

Source: Acta Biochimica et Biophysica Sinica - April 26, 2018 Category: Biochemistry Authors: Ding J, Zhao Z, Song J, Luo B, Huang L Tags: Acta Biochim Biophys Sin (Shanghai) Source Type: research