Cytogenetic profile of Moroccan pediatric acute lymphoblastic leukemia (ALL): analysis of 155 cases with review of literature

Acute lymphoblastic leukemia (ALL) is the commonest malignancy in children, with a peak incidence of 2 to 3 years, accounting for almost 30% of all cancers in this age group.It is well established that the identification of cytogenetic abnormalities is highly relevant for prognosis and therapeutic decisions in ALL.The purpose of this study is to define the frequency of recurrent chromosomal abnormalities of ALL in Moroccan patients referred exclusively to BIOLAB laboratory from the children hospital of Rabat over a period of 4 years and compare our findings to the literature.

Source: Clinical Lymphoma, Myeloma and Leukemia - April 24, 2018 Category: Hematology Authors: Z. Takki Chebihi, A. Belkhayat, E. Chadli, L. Hilal, H. Skhoun, L. Hessissen, M. El Khorassani, M. El Kababri, A. Kili, M. Khattab, Y. Bakri, N. Dakka Source Type: research