Chemical probes and drug leads from advances in synthetic planning and methodology

Nature Reviews Drug Discovery 17, 333 (2018). doi:10.1038/nrd.2018.53 Authors: Christopher J. Gerry & Stuart L. Schreiber Screening of small-molecule libraries is a productive method for identifying both chemical probes of disease-related targets and potential starting points for drug discovery. In this article, we focus on strategies such as diversity-oriented synthesis that aim to explore novel areas of chemical space efficiently by
Source: Nature Reviews Drug Discovery - Category: Drugs & Pharmacology Authors: Tags: Review Source Type: research