Malaria: Clues to vaccine design
Nature Reviews Drug Discovery 17, 316 (2018).
doi:10.1038/nrd.2018.57
Author: Sarah Crunkhorn
Vaccination with attenuated Plasmodium falciparum sporozoites (PfSPZs) can induce robust immune responses. However, the specific mediators of this protective immune response remain undefined. To investigate this, Seder and colleagues first isolated monoclonal antibodies directed against the Pf circumsporozoite protein (PfCSP) — which covers the
Source: Nature Reviews Drug Discovery - Category: Drugs & Pharmacology Authors: Sarah Crunkhorn Tags: Research Highlight Source Type: research