Evolving Paradigms for Stroke Prevention in Patients with Atrial Fibrillation

Stroke is the most dreaded complication of atrial fibrillation (AF) and its prevention remains central to the management of this common arrhythmia. The approach to preventing and managing stroke in AF patients has evolved significantly over the past decade. Some of the major innovations in this field include better definition of the at risk population, availability of new anticoagulant agents and, more recently, interventional therapies that target the left atrial appendage. In this well-rounded review, Stock and Malm comprehensively discuss all aspects of stroke prevention and management in AF patients [1].
Source: Trends in Cardiovascular Medicine - Category: Cardiology Authors: Source Type: research

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Oral anticoagulants are prescribed for stroke prophylaxis in patients with atrial fibrillation, which is the most common heart arrhythmia worldwide. The vitamin K antagonist (VKA) warfarin is a long-establishe...
Source: BMC Health Services Research - Category: General Medicine Authors: Tags: Research article Source Type: research
Int J Angiol DOI: 10.1055/s-0040-1705111Atrial fibrillation is a common arrhythmia which may cause symptoms that significantly impact quality of life and is associated with increased risk of stroke, heart failure, and sudden death. Over the past three decades many surgical techniques as well as catheter-bases procedures have been developed to treat atrial fibrillation. In this review we describe the indications, treatments, outcomes, surgical techniques, and technical advances reported in the literature. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of conten...
Source: International Journal of Angiology - Category: Cardiology Authors: Tags: Invited Papers Source Type: research
Conclusion: A frequent ablation device position changing during the surgery makes it possible to achieve complete left atrial posterior wall and pulmonary veins isolation. An increased number of applications allows to avoid a false positive transmural damage assessment showed by impedance drop. Also, frequent position changing of the ablation device and increased number of applications do not affect the number of postoperative complications.
Source: Revista Brasileira de Cirurgia Cardiovascular - Category: Cardiovascular & Thoracic Surgery Source Type: research
Tatjana PS Abstract Atrial fibrillation (AF) is the most common cardiac arrhythmia and is associated with increased risk of death, stroke and heart failure. The prevalence and incidence of AF is increasing due to better overall medical treatment, longer survival and increasing incidence of cardiometabolic and lifestyle risk factors. Treatment of AF and AF-related complications significantly increase health-care costs. In addition, use of conventional rhythm control strategies (i.g. antiarrhyhtmic drugs and catheter-ablation) is associated with limited efficacy for sinus rhythm maintenance and serious adverse effe...
Source: Polish Heart Journal - Category: Cardiology Authors: Tags: Kardiol Pol Source Type: research
By KOUSIK KRISHNAN, MD As many industries and individuals are struggling publicly with burnout, a new study from the European Journal of Preventative Cardiology links the “burnout syndrome” with atrial fibrillation (afib). The findings are both interesting and valuable. In general, the public benefits from anything that can raise awareness of heart disease, because early intervention directly impacts improved patient outcomes. However, headlines that describe afib as a “deadly irregular heartbeat” go too far in the name of public awareness. The truth is,...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: Medical Practice Patients afib atrial fibrillation cardiac care irregular heartbeat Kousik Krishnan Source Type: blogs
mmittee of the Council on Clinical Cardiology; Council on Arteriosclerosis, Thrombosis and Vascular Biology; Council on Cardiovascular and Stroke Nursing; and Council on Lifestyle and Cardiometabolic Health Abstract Atrial fibrillation (AF), the most common sustained cardiac arrhythmia, is associated with substantial morbidity, mortality, and healthcare use. Great strides have been made in stroke prevention and rhythm control strategies, yet reducing the incidence of AF has been slowed by the increasing incidence and prevalence of AF risk factors, including obesity, physical inactivity, sleep apnea, diabetes melli...
Source: Circulation - Category: Cardiology Authors: Tags: Circulation Source Type: research
AbstractAtrial fibrillation is the most common arrhythmia and its prevalence is expected to further increase. Patients with atrial fibrillation have an increased risk of stroke (fivefold increased risk), heart failure, and death. In patients with non-valvular atrial fibrillation, the most recent guidelines recommend the use of the CHA2DS2-VASc (congestive heart failure, arterial hypertension, age  >  75 years, diabetes mellitus, stroke/transient ischemic attack, vascular disease, age 65–74 years, sex category) scoring system to identify those who may benefit from oral anticoagulant treatmen...
Source: Internal and Emergency Medicine - Category: Emergency Medicine Source Type: research
New Brunswick, NJ, February 25, 2020 — Johnson &Johnson (NYSE: JNJ) today announced that the Janssen Pharmaceutical Companies of Johnson &Johnson, in collaboration with Apple, opened enrollment for the Heartline™ Study. The study is designed to explore if the Heartline™ Study app on iPhone and heart health features on Apple Watch can improve health outcomes, including reducing the risk of stroke, with earlier detection of atrial fibrillation (AFib). AFib, a common form of irregular heart rhythm, is a leading cause of stroke in the U.S. To enroll in the Heartline™ Study, individuals must be a...
Source: Johnson and Johnson - Category: Pharmaceuticals Tags: Innovation Source Type: news
by Jieyun Bai, Andy Lo, Patrick A. Gladding, Martin K. Stiles, Vadim V. Fedorov, Jichao Zhao Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia and is a major cause of stroke and morbidity. Recent genome-wide association studies have shown that paired-like homeodomain transcription factor 2 (Pitx2) to be strongly associated with AF. However, the mechanisms underlying Pitx2 modulated arrhythmogenesis and variable effectiveness of antiarrhythmic drugs (AADs) in patients in the presence or absence of impaired Pitx2 expression remain unclear. We have developed multi-scale computer models, ranging from a ...
Source: PLoS Computational Biology - Category: Biology Authors: Source Type: research
;li B Abstract BACKGROUND: Long-term ECG recording is a commonly used test. However, there are no clear guidelines on who should be examined using this method, and we lack an overview of the results of testing and their therapeutic implications. MATERIAL AND METHOD: All long-term ECG recordings performed at Sørlandet Hospital Arendal in the period 2017-18 were included in the study. The tests were identified by searching the medical records system for relevant procedure codes, and all medical records related to the test were subsequently reviewed. Patient characteristics, referrer, indication, results,...
Source: Tidsskrift for den Norske Laegeforening - Category: General Medicine Authors: Tags: Tidsskr Nor Laegeforen Source Type: research
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