Hypoxia induced EMT: A review on the mechanism of tumor progression and metastasis in OSCC

Head and neck cancer encompasses the cancer of the oral cavity, paranasal sinuses, pharynx, and larynx [1,2]. Head and Neck cancer, which develops at the lips, tongue, salivary glands, gingiva, floor of the mouth, oropharynx, buccal surfaces and other intra-oral locations [3], is the sixth most common cancer in the world [4]. The GLOBOCAN 2012 report indicated an estimated 300,400 new cases and 145,400 deaths due to oral cancer, with the highest rates being found in Melanesia and South-Central and Eastern Asia [5,6].
Source: Oral Oncology - Category: Cancer & Oncology Authors: Tags: Review Source Type: research