A 24-Year-Old Woman With Photophobia: USMLE Question A 24-Year-Old Woman With Photophobia: USMLE Question
A 24-year-old woman presents due to headache, fever, neck stiffness, and photophobia. What's the immediate next step in her management?Osmosis
Abstract Neuropsychiatric adverse events (NPAEs) observed with the integrase strand transfer inhibitor (INSTI) dolutegravir (DTG) are usually mild to moderate. The most prevalent symptoms are insomnia and sleep disorders, but the spectrum also includes dizziness, anxiety, depression, headache, paraesthesia, muscle-skeletal pain, poor concentration, and slow thinking. In recent cohort studies involving>6400 patients in different countries, discontinuation rates due to NPAEs were observed in around 3.5% (range, 1.4-7.2%) of subjects treated with DTG. These rates have been higher than those seen in randomized clin...
Publication date: Available online 23 March 2019Source: Journal of Electroanalytical ChemistryAuthor(s): N. Lavanya, C. SekarAbstractSerotonin is a monoamine neurotransmitter produced from tryptophan and abnormal levels of these molecules have been associated with several disorders, notably depression, migraine, bipolar disorder, anxiety and schizophrenia. In the present work, we have developed a novel electrochemical sensor using SnO2-SnS2 nanocomposite for selective and simultaneous determination of depression biomarkers serotonin (SE) and tryptophan (Trp) in the presence of ascorbic acid (AA). The SnO2-SnS2 composite pr...
(The Endocrine Society) For migraine sufferers with obesity, losing weight can decrease headaches and improve quality of life, researchers from Italy and the United States report. The results of their meta-analysis will be presented Saturday, March 23 at ENDO 2019, the Endocrine Society's annual meeting in New Orleans, La.
ConclusionRecurrence of medulloblastoma may occur despite more than 15 years of complete remission.Because of this fact it is mandatory to continue the follow-up of these patients.Aggressive management of recurrence is recommended in absence of disease dissemination.
AbstractPurpose of reviewThis review seeks to establish the role of beta-blockers (B-adrenergic receptor antagonists) in the pathophysiology of migraine prophylaxis, compare the efficacy of this group of medications with other common prophylactic agents, and also explore the relative benefits of using individual beta-blockers compared with others.Recent findingsNew evidence supports beta-blockers having several mechanisms of action in migraine prophylaxis. Numerous trials reveal significant clinical differences between various beta-blockers in migraine prophylaxis and that commonly used doses of beta-blockers are not optim...
Condition: Headache, Migraine Interventions: Drug: Maxipost; Drug: Saline Sponsor: Danish Headache Center Recruiting
Conditions: Hemodynamics of Cranial Arteries; Headache; Cerebral Blood Flow Interventions: Drug: Levcromakalim; Drug: Saline Sponsor: Danish Headache Center Recruiting
Conditions: Dizziness; Nausea; Headache; Confusion Interventions: Device: Otoband; Device: Otoband sham Sponsor: Otolith Labs Not yet recruiting
Elisabeth Colon, Allison Ludwick, Sophie L. Wilcox, Andrew M. Youssef, Amy Danehy, Damien A. Fair, Alyssa A. Lebel, Rami Burstein, Lino Becerra, David Borsook
ConclusionsFindings suggest that self-harm behavior and psychiatric disorders are associated with increased ED utilization for subsequent chronic disease-related ED utilization. Chronic disease among adolescent psychiatric patients should be attended to, potentially involving new models of clinical follow-up care.