Chest Wall Resection for Recurrent Breast Cancer Chest Wall Resection for Recurrent Breast Cancer

The utility of full-thickness chest wall resection for recurrent breast cancer has been debated. Is it time for a new way of thinking?Annals of Surgery
Source: Medscape Today Headlines - Category: Consumer Health News Tags: General Surgery Journal Article Source Type: news

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Background: Despite pharmacological treatment, chemotherapy-induced nausea and vomiting (CINV) are observed in patients. Objective: This quasi-randomized controlled pilot study evaluated the feasibility and preliminary effects of massage and inhalation aromatherapies on chemotherapy-induced acute nausea/vomiting. Methods: Seventy-five patients with breast cancer were randomly grouped into 1 of 3 groups: massage (n = 25), inhalation (n = 25), and control (n = 25). The patients in the massage group received 20-minute aromatherapy foot massage, whereas those in the inhalation group received 3-minute inhalation aromath...
Source: Cancer Nursing - Category: Nursing Tags: Articles Source Type: research
Conclusions Voluntary participation in breast health–seeking behaviors is a culturally sensitive topic. The qualitative methodology allowed this sensitive topic and its different aspects to be explored. The findings indicated that the major source of support for women was their husband’s behavior toward breast health–seeking actions. Family cohesion and love among couples were identified as strong determinant factors pertaining to husband’s supportive behaviors. Implications for Practice The study findings provided deeper understanding about the effective factors related to a husband’s ro...
Source: Cancer Nursing - Category: Nursing Tags: Articles Source Type: research
Conclusions: Breast, prostate, and colorectal cancer survivors seem to use different coping strategies that varied throughout the survivorship trajectory. Breast cancer survivors highlighted the importance of accepting their diagnosis and engaging in physical activities that provided social and emotional support. Personality seemed to have a significant effect on coping for prostate cancer survivors. Colorectal cancer survivors emphasized the importance of seeking information to master self-management and return to social activities. Implications for Practice: Understanding coping strategies, during the survivorship t...
Source: Cancer Nursing - Category: Nursing Tags: Articles: Online Only Source Type: research
Peng Liu, Hailin Tang, Cailu Song, Jin Wang, Bo Chen, Xiaojia Huang, Xiaoqing Pei, Longzhong Liu
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 21 August 2018Source: Biochimica et Biophysica Acta (BBA) - Reviews on CancerAuthor(s): Michael Mc Kenna, Sarah McGarrigle, Graham P. PidgeonAbstractThe PI3K/Akt/mTOR pathway plays a role in various oncogenic processes in breast cancer and key pathway aberrations have been identified which drive the different molecular subtypes. Early drugs developed targeting this pathway produced some clinical success but were hampered by pharmacokinetics, tolerability and efficacy problems. This created a need for new PI3K pathway-inhibiting drugs, which would produce more robust results allowing incor...
Source: Biochimica et Biophysica Acta (BBA) Reviews on Cancer - Category: Cancer & Oncology Source Type: research
This paper proposes a segmentation-free radiomics method to classify malignant and benign breast tumors with shear-wave elastography (SWE) data. The method is targeted to integrate the advantage of both SWE in providing important elastic with morphology information and convolutional neural network (CNN) in automatic feature extraction and accurate classification. Compared to traditional methods, the proposed method is designed to directly extract features from the dataset without the prerequisite of segmentation and manual operation. This can keep the peri-tumor information, which is lost by segmentation-based methods. Wit...
Source: IEEE Transactions on Biomedical Engineering - Category: Biomedical Engineering Source Type: research
This study warrants further research to explore the genotoxicity of SnO2 NPs in different types of cancer cells.Graphical abstract
Source: Colloids and Surfaces B: Biointerfaces - Category: Biochemistry Source Type: research
ConclusionsA series of studies provide detailed information to understand lncRNA AFAP1-AS1 role in various human cancers. LncRNA AFAP1-AS1 is an oncogene in tumors that have been studied so far, and it may act as a useful tumor biomarker and therapeutic target.
Source: Pathology Research and Practice - Category: Pathology Source Type: research
ConclusionQHF can prevent the proliferation, migration, and invasion of MCF-7 cells by inhibiting the HGF/c-Met and its downstream PI3K/Akt and MAPK/ERK signaling pathways; Thereby down-regulating the expresssion of HGF, p-Met, p-ERK1, p-ERK2, p-Akt, MMP-2, MMP-9, and VEGF.
Source: Chinese Herbal Medicines - Category: Complementary Medicine Source Type: research
Publication date: 1 December 2018Source: Sensors and Actuators B: Chemical, Volume 275Author(s): Girija Gaur, Shuren Hu, Raymond L. Mernaugh, Ivan I. Kravchenko, Scott T. Retterer, Sharon M. WeissAbstractHighly sensitive detection of heat denatured Herceptin® (trastuzumab), an important monoclonal antibody used in breast cancer therapeutics, is demonstrated using transverse magnetic (TM) mode suspended microring resonators (MRRs). The suspended MRRs are surface functionalized with a single chain fragment variable (scFv) recombinant antibody molecule (designated 2B4) that enables selective capture of denatured Herceptin...
Source: Sensors and Actuators B: Chemical - Category: Chemistry Source Type: research
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