PARP-1 may be key to effectiveness of PARP inhibitors, and now researchers can image it

(University of Pennsylvania School of Medicine) Penn Medicine researchers have used CRISPR/Cas9 gene editing technology to isolate a key genetic feature that could cause resistance to PARP inhibitors in patients with ovarian cancer -- and they've also proven they have a way to see that feature using PET imaging.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news