Is ciliary Hedgehog signalling dispensable in the kidneys?

Is ciliary Hedgehog signalling dispensable in the kidneys?Is ciliary Hedgehog signalling dispensable in the kidneys?, Published online: 26 April 2018; doi:10.1038/s41581-018-0014-6An unbiased functional gene knockout screen to identify genes implicated in Hedgehog signalling in primary cilia detected most components of the ciliary machinery and ciliopathy-associated genes, but no kidney-related ciliopathy genes. The 472 hits are a tremendous resource for identifying potential ciliopathy genes and for analysing ciliary function and signalling pathways.
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Source Type: research