Ask D?Mine: Get Answers to All Your Diabetes Questions!

Our weekly advice column at DiabetesMine provides answers to all sorts of questions about life with diabetes, from patients in the trenches.
Source: Diabetes Mine - Category: Endocrinology Authors: Source Type: blogs

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Authors: Fukaishi T, Minami I, Masuda S, Miyachi Y, Tsujimoto K, Izumiyama H, Hashimoto K, Yoshida M, Takahashi S, Kashimada K, Morio T, Kosaki K, Maezawa Y, Yokote K, Yoshimoto T, Yamada T Abstract We herein report a case of a 28-year-old man with generalized lipodystrophy-associated progeroid syndrome treated by leptin replacement. He showed symptoms of generalized lipodystrophy around onset of puberty. His body mass index was 11.9 kg/m2, and he had a short stature, birdlike facies, dental crowding due to micrognathia, partial graying and loss of hair, and a high-pitched voice, all of which are typical features o...
Source: Endocrine Journal - Category: Endocrinology Tags: Endocr J Source Type: research
High blood pressure? There ’s an app for that. Diabetes? There’s an app for that, too. Want to quit smoking? Keep track of your exercise? Is your anxiety getting the better of you? There are apps for all of those health issues, hundreds of thousands of apps. Developers at Blue Shield of California have rolled out a ne w, enhanced Wellvolution website — Wellvolution Next — that brings together roughly 40 of the best “digital therapeutics” applications in one place where members can…
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
Publication date: Available online 12 November 2019Source: Life SciencesAuthor(s): Eman Soliman, Shereen F. Behairy, Nabila N. El-maraghy, Shimaa M. ElshazlyAbstractPeroxisome proliferator-activated receptor γ (PPAR-γ) agonist, pioglitazone, is used clinically to improve the glycemic state in patients with type-2 diabetes mellitus. Independent of its blood glucose-lowering properties, pioglitazone ameliorates different cardiovascular disorders. The aim of the present study was to investigate the effect of pioglitazone on cardiovascular complications of N-nitro-L-arginine methyl ester (L-NAME)-induced hypertensi...
Source: Life Sciences - Category: Biology Source Type: research
Publication date: Available online 12 November 2019Source: Life SciencesAuthor(s): Hauwa’u Yakubu Bako, Mohammed Auwal Ibrahim, Muhammad Sani Isah, Sani IbrahimAbstractAimsChronic inflammation is associated with the production of high levels of proinflammatory cytokines via the JAK-STAT and NF-κB signalling pathways which are known to be inhibited by tofacitinib and aspirin respectively. High levels of these cytokines increase the synthesis of suppressors of cytokines (SOCS), which at high levels inhibit insulin signalling leading to insulin resistance. The effects of tofacitinib and aspirin on the degree of in...
Source: Life Sciences - Category: Biology Source Type: research
Publication date: Available online 12 November 2019Source: Life SciencesAuthor(s): Younis Ahmad Hajam, Seema RaiAbstractAimsThe present study was designed to ameliorate the integrated efficacy of exogenous melatonin and insulin on tissue biochemical, serological, histopathological architecture and receptor expression of melatonin (MT1, MT2) and insulin receptor (IR) expression against the hepatic injury in diabetic rats. Materials and Method; the rats were randomly allocated into nine different experimental groups. Diabetes was induced by streptozotocin (15mg/kg) for 6 days. Rats having blood glucose level above 250mg/dl w...
Source: Life Sciences - Category: Biology Source Type: research
Publication date: Available online 13 November 2019Source: PeptidesAuthor(s): Nigel Irwin, Victor A. Gault, Finbarr P.M. O’Harte, Peter R. FlattAbstractGastric inhibitory polypeptide (GIP) is a 42 amino acid hormone secreted from intestinal K-cells in response to nutrient ingestion. Despite a recognised physiological role for GIP as an insulin secretagogue to control postprandial blood glucose levels, growing evidence reveals important actions of GIP on adipocytes and promotion of fat deposition in tissues. As such, blockade of GIP receptor (GIPR) action has been proposed as a means to counter insulin resistance, and...
Source: Peptides - Category: Biochemistry Source Type: research
Overly expensive insulin could be a thing of the past – and life-changing news – for millions of diabetics under a plan launched by the World Health Organization (WHO) on Wednesday to diversify production globally, just ahead of World Diabetes Day.
Source: UN News Centre - Health, Poverty, Food Security - Category: International Medicine & Public Health Source Type: news
Condition:   Diabetic Retinopathy Intervention:   Sponsors:   Acer Being Health Inc.;   National Taiwan University Hospital Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Type 1 Diabetes Intervention:   Device: eversense Sponsors:   Meir Medical Center;   DYN Diagnostic LTD Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Type 2 Diabetes Mellitus Interventions:   Drug: DBPR108; Placebo matching sitagliptin;   Drug: Placebo matching DBPR108; Sitagliptin; DBPR108;   Drug: Placebo matching DBPR108; Placebo matching sitagliptin; DBPR108 Sponsor:   CSPC ZhongQi Pharmaceutical Technology Co., Ltd. Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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