Triethylene glycol dimethacrylate impairs bioenergetic functions and induces oxidative stress in mitochondria via inhibiting respiratory Complex I

Dental composite resins are commonly used to restore structural tooth damages. The development of resin-based composites (RBCs) has resulted in esthetically pleasing and long lasting dental restorations [1]. Recently, biocompatibility of the filling materials has become a clinically relevant issue [2]. Most RBCs contain strongly viscous major monomers and co-monomers of lower viscosity such as triethylene glycol dimethacrylate (TEGDMA) [3 –5]. Incomplete RBC polymerization may lead to an undesired leaching of the monomers into the oral tissues [6,7].
Source: Dental Materials - Category: Materials Science Authors: Source Type: research