Genetic variation in cytokine genes and risk for transition to psychosis among individuals at ultra-high risk

Cytokines play important neurodevelopmental roles in the brain and the levels at which they are expressed are, in part, dependent on an individual's genetic background (Kronfol and Remick, 2000). A number of genetic studies have demonstrated associations between common variation in genes encoding inflammatory cytokines and schizophrenia in ethnically diverse populations (Butler et al., 2016). However, analogous genetic studies have not been conducted within an ultra-high risk (UHR) for psychosis population.

Source: Schizophrenia Research - September 12, 2017 Category: Psychiatry Authors: Chad A. Bousman, Tae Young Lee, Minah Kim, Junhee Lee, Md Shaki Mostaid, Minji Bang, Suk Kyoon An, Ian P. Everall, Christos Pantelis, Jun Soo Kwon Tags: Letter to the Editor Source Type: research