The effects of curcumin on brain-derived neurotrophic factor and cognition in schizophrenia: A randomized controlled study

Curcumin is a polyphenolic compound derived from the spice turmeric (Curcuma longa) with potential as a complementary treatment for people with schizophrenia. In preclinical studies, curcumin has been reported to have anti-oxidant, anti-inflammatory, neuroprotective, and pro-cognitive properties, as well as increased levels of brain-derived neurotrophic factor (BDNF) (Dong et al., 2012; Fanaei et al., 2016; Motaghinejad et al., 2017). The effects of curcumin on BDNF and neurocognition are particularly relevant for schizophrenia as well-documented lower levels of BDNF and neurocognitive deficits have been reported (Green et al., 2011).
Source: Schizophrenia Research - Category: Psychiatry Authors: Tags: Letter to the Editor Source Type: research