Increased resting-state global functional connectivity density of default mode network in schizophrenia subjects treated with electroconvulsive therapy

Modified electroconvulsive therapy (MECT) has been widely applied to help treat schizophrenia patients who are treatment-resistant to pharmaceutical therapy. Although the technique is increasingly prevalent, the underlying neural mechanisms have not been well clarified. We conducted a longitudinal study to investigate the alteration of global functional connectivity density (gFCD) in schizophrenia patients undergoing MECT using resting state fMRI (functional magnetic resonance imaging). Two groups of schizophrenia inpatients were recruited.
Source: Schizophrenia Research - Category: Psychiatry Authors: Source Type: research