Discontinuing antipsychotic treatment after a first-episode of psychosis: Who, when and how?

Deciding how long antipsychotic treatment should be maintained in patients who respond favourably after a single psychotic episode remains a controversial and unresolved matter, of great clinical importance. On the one hand, it could be argued that, given the very high rates of relapse after antipsychotic discontinuation and the serious consequences associated with illness recurrence, indefinite maintenance treatment should be advised for all patients who have benefitted from treatment and where side-effects are not severe.
Source: Schizophrenia Research - Category: Psychiatry Authors: Tags: Invited commentary Source Type: research
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