Relationship between hallucination proneness and musical aptitude is mediated by microstructure in the corpus callosum

Poor interhemispheric communication is reported in schizophrenia patients (Endrass et al., 2002) and offers a potential explanation for the misattribution of internal events to external sources, which is a dominant theory for the genesis of auditory verbal hallucinations (AVH). Consistent with this, the corpus callosum (CC), the white matter (WM) tract connecting the two brain hemispheres, is reduced in volume in schizophrenia patients (Shenton et al., 2001). Furthermore, the WM integrity metric derived from diffusion tensor imaging (DTI), fractional anisotropy (FA) (Beaulieu, 2002), is reduced within the CC of schizophrenia patients (Keshavan et al., 2002).
Source: Schizophrenia Research - Category: Psychiatry Authors: Tags: Letter to the Editor Source Type: research