Frontal and temporal cortical volume, white matter tract integrity, and hemispheric asymmetry in schizotypal personality disorder

Abnormalities in temporal and frontal cortical volume, white matter tract integrity, and hemispheric asymmetry have been implicated in schizophrenia-spectrum disorders. Schizotypal personality disorder can provide insight into vulnerability and protective factors in these disorders without the confounds associated with chronic psychosis. However, multimodal imaging and asymmetry studies in SPD are sparse. Thirty-seven individuals with SPD and 29 healthy controls (HC) received clinical interviews and 3T magnetic resonance T1-weighted and diffusion tensor imaging scans.

Source: Schizophrenia Research - February 14, 2018 Category: Psychiatry Authors: Chi C. Chan, Philip R. Szeszko, Edmund Wong, Cheuk Y. Tang, Caitlin Kelliher, Justin D. Penner, M. Mercedes Perez-Rodriguez, Daniel R. Rosell, Margaret McClure, Panos Roussos, Antonia S. New, Larry J. Siever, Erin A. Hazlett Source Type: research