Further evidence for depletion of peripheral blood natural killer cells in patients with schizophrenia: A computational deconvolution study

Dysregulation of innate and adaptive immunity is increasingly being recognized as one of core characteristics of schizophrenia pathophysiology. Several studies have revealed that patients with schizophrenia present various alterations in the levels of distinct leukocyte subpopulations. However, studies addressing this point have provided mixed results. Therefore, in this study we translated a computational deconvolution algorithm in order to estimate counts of distinct leukocyte subpopulations in peripheral blood of patients with schizophrenia.

Source: Schizophrenia Research - April 19, 2018 Category: Psychiatry Authors: Pawe ł Karpiński, Jerzy Samochowiec, Dorota Frydecka, Maria M. Sąsiadek, Błażej Misiak Source Type: research