Losartan in combination with propranolol slows the aortic root dilatation in neonatal Marfan syndrome

In this report, a combination of losartan and propranolol reduced the aortic root dilatation rate after three months of losartan therapy. Genetic analysis in this patient revealed a mutation in exon 25 of the FBN1 gene, which typically results in a shorter life expectancy.

Source: Pediatrics and Neonatology - August 16, 2017 Category: Perinatology & Neonatology Authors: Lu-Hang Liu, Shan-Miao Lin, Dar-Shong Lin, Ming-Ren Chen Tags: Short Communication Source Type: research