Successful treatment of a hepatic-hemangioendothelioma infant presenting with hypothyroidism and tetralogy of Fallot

Infantile hepatic hemangioendothelioma (IHHE), although rare, is one of the most common vascular tumors of the liver in children.1,2 Though the tumors are histologically benign, they occasionally cause life-threatening complications, such as cardiac failure, coagulation disorder, respiratory distress and, sometimes, hypothyroidism.1 Prednisolone was mainly used for treatment of symptomatic IHHE, but recently, several case reports showed the therapeutic effects of propranolol for IHHE.3

Source: Pediatrics and Neonatology - August 22, 2017 Category: Perinatology & Neonatology Authors: Akari Takai, Tomoko Iehara, Mitsuru Miyachi, Yoshiki Okumura, Tatsuji Hasegawa, Sachiko Tokuda, Kazuyuki Ikeda, Masaaki Yamagishi, Tatsuro Tajiri, Hajime Hosoi Tags: Short Communication Source Type: research