Marked elevation of circulating CD19+CD38hiCD24hi transitional B cells give protection against neonatal sepsis

Adequate functions of immunoregulation, mediated by regulatory cells such as IL-10 producing CD19+CD38hiCD24hi transitional B cells (Trans), play an important role in control of excessive inflammatory response. Yet, the role of Trans in neonatal sepsis is incompletely understood. We investigated the role of Trans in late-onset sepsis (LOS).

Source: Pediatrics and Neonatology - November 24, 2017 Category: Perinatology & Neonatology Authors: Sitao Li, Fei Ma, Hu Hao, Desheng Wang, Yu Gao, Jialiang Zhou, Fei Li, Hung-Chih Lin, Xin Xiao, Qiyi Zeng Tags: Original Article Source Type: research