Re-randomization increased recruitment and provided similar treatment estimates as parallel designs in trials of febrile neutropenia

Re-randomization trials allow patients to be re-enrolled for multiple treatment episodes. However, it remains uncertain to what extent re-randomization improves recruitment compared to parallel group designs or whether treatment estimates might be affected.

Source: Journal of Clinical Epidemiology - February 8, 2018 Category: Epidemiology Authors: Brennan C. Kahan, Tim P. Morris, Erica Harris, Rupert Pearse, Richard Hooper, Sandra Eldridge Tags: Original Article Source Type: research