Dermtreat Appoints Nishan de Silva, M.D., as CEO; Establishes North American Headquarters in San Diego
President, Research &Development, and Founder Jens Hanson, Ph.D., to lead R&D operations in Denmark SAN DIEGO and COPENHAGEN, Denmark, April 25, 2018 -- (Healthcare Sales &Marketing Network) -- Dermtreat, a clinical-stage biopharmaceutical company fo... Biopharmaceuticals, Dermatology, Personnel Dermtreat, Rivelin, clobetasol, oral lichen planus
CONCLUSIONS: During antihypertensive treatment, several dermatological reactions may occur. Clinicians should inform their patients of the increased risk of cutaneous lesions associated with the use of these drugs, and perform periodic examination of the skin. PMID: 31195782 [PubMed - as supplied by publisher]
ConclusionThese lichenoid lesions were solitary plaques located most commonly on the tongue and gingiva, common sites for leukoplakia with 54.1% exhibiting OED. As such, these lesions more likely represent leukoplakia with a LHR rather than OLP. Clinicopathologic correlation is essential for accurate diagnosis.
We present a case of PCG in a 13 year old female patient which clinically presented as generalized desquamative gingivitis involving the facial aspects of the attached and marginal gingiva that persisted despite substituting to a non flavored dentifrice and failure to elicit any suspected drug or food allergies. Dermatologic patch testing proved positive for Iodopropynyl Butylcarbamate (IPBC), a water based preservative or biocide used in personal care products. Microscopically, there was an intense inflammatory infiltrate in the lamina propria composed predominantly of mature plasma cells. Immunohistochemistry and in situ...
ConclusionSince CUS has overlapping clinical, histological, and immunofluorescence features with lichen planus and vesiculobullous diseases, clinicians and pathologists should consider this unusual, but significant, entity whenever oral ulcerative diseases with mixed features are encountered.
This study aimed to evaluate the immunohistochemical expression of thyroid-stimulating hormone (TSH) and thyroid-stimulating hormone receptor (TSHR) in healthy oral mucosa and in OLP lesions of individuals with and without HT.
Oral cancer may be preceded by Potentially malignant lesions such as leukoplakia, erythroplakia, stomatitis nicotina, oral submucous fibrosis (OSMF) and erosive lichen planus(LP). Oral Epithelial dysplasia (OED) is an important predictor of malignant potential. According to WHO 2017, the three tiered grading reliability can be improved by Binary grading system of high&low risk. So the aim of this retrospective study was verify the applicability of the binary grading system for OED in our institution.
Verruciform Xanthoma (VX) is a benign condition occurring primarily in the oral cavity with some lesions also found on the genital mucosa or skin. VX occurs primarily in the fifth decade of life and shows a slight male predilection. This lesion generally presents as a papillary or rough-surfaced, painless, well-demarcated lesion, ranging from white, yellow-white, to orange in color. The etiology of VX is still largely unknown and definitive diagnosis is made based on histology. This lesion is thought to correlate with localized trauma or chronic inflammatory conditions such as lichen planus, lupus, epithelial dysplasia, pe...
This study will review a case series of CUS and assess if the entity is more similar to lichen planus or vesiculobullous diseases.
Oral epithelial dysplasia (OED) and oral squamous cell carcinomas (SCCAs) often exhibit a lymphocytic host response (LHR) present as a band at the epithelium-connective tissue interface. Because these are often diagnosed as dysplasia with lichenoid mucositis or lichenoid dysplasia, clinicians assume that such lesions represent dysplasia or SCCA arising within lesions of oral lichen planus (OLP). If the clinical lesion is a solitary plaque, the diagnosis of plaque-type OLP may be made. Lichenoid lymphocytic reactions are not specific to OLP and may be seen in drug-induced, contact hypersensitivity reactions and other conditions.
Authors: Manczyk B, Gołda J, Biniak A, Reszelewska K, Mazur B, Zając K, Bińczak P, Chomyszyn-Gajewska M, Oruba Z Abstract The pathogenesis of oral lichen planus (OLP) remains to be fully elucidated; however, certain psychoneurological factors may influence the onset and exacerbation of OLP. The aim of the present study is to evaluate the intensity of negative emotions in patients with OLP. A cross-sectional, questionnaire-based study was performed. The sample consisted of 52 subjects, comprising 26 patients with OLP (OLP group) and 26 controls (CTRL group). The Depression Anxiety Stress Scale 21 (DASS-21) was us...