Transient global cerebral ischemia differentially affects cortex, striatum and hippocampus in Bilateral Common Carotid Arterial occlusion (BCCAo) mouse model

This study shows a region-specific temporal molecular response to global ischemia in the brain, which is important to get better insight into the pathophysiology since each region consists of different subsets of neurons that are having different susceptibility and tolerance pattern/level. This insight into a temporally different ischemic response and the underlying molecular basis might help in strategizing the effective therapeutics against stroke. Graphical abstract
Source: Journal of Chemical Neuroanatomy - Category: Neuroscience Source Type: research