Parental genetic material and oxygen concentration affect hatch dynamics of mouse embryo in vitro.

CONCLUSION: Both parental genetic material and O2 concentration, as the representative of intrinsic and extrinsic factors respectively, have significant impacts on mouse preimplantation development and subsequent hatch dynamics, probably by regulating the gene expression involving in MAPK pathway and superoxide dismutase family to control embryonic cell proliferation and allocation of ICM cells.
PMID: 29679980 [PubMed - in process]

Source: Reproductive Biology - April 21, 2018 Category: Reproduction Medicine Authors: Zhan S, Cao S, Du H, Sun Y, Li L, Ding C, Zheng H, Huang J Tags: Reprod Biol Endocrinol Source Type: research