Correlation of Reflectance Confocal Microscopy and Dermatopathology Findings in a Case of Acrodermatitis Chronica Atrophicans

In this study, we report reflectance confocal microscopy (RCM) findings in a case of ACA. RCM examination revealed a flattened surface with broadened skin folds, a flattened dermoepidermal junction with few papillae and less bright basal cells and multiple small bright reflecting spots in the dermis. To the best of our knowledge, this is the first description of the RCM findings in this disorder.
Source: The American Journal of Dermatopathology - Category: Pathology Tags: Extraordinary Case Report Source Type: research

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Conclusions: Despite raising awareness of Lyme borreliosis, late forms of the disease such as ACA are still observed. Acrodermatitis chronica atrophicans skin lesions may be located in non-characteristic areas, e.g. abdominal skin. Symptoms are not irritating or painful, therefore patients do not seek medical help. The effect of antibiotic treatment varies. PMID: 30429707 [PubMed]
Source: Advances in Dermatology and Allergology - Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research
Amy B. Scher’s “This Is How I Save My Life” is the true story of a fiery young woman diagnosed with late-stage, chronic Lyme disease whose journey takes her from near-death in California to a trip around the world in search of her ultimate salvation. This excerpt coincides with the book’s release in paperback from Gallery Books, an imprint CBS sister company Simon &Schuster. I am twenty-eight years old when I arrive in magnificent India. I am here with my parents, an updated vaccine record, and a visa, searching for something I cannot find at home: a cure. In a tiny hospital on the outskirts of ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health Simon and Schuster Source Type: news
In conclusion, tick-mediated infections can trigger GA in some cases, while correlation of either Borrelia or Chlamydiales with morphea is unlikely. PMID: 29110020 [PubMed - as supplied by publisher]
Source: Acta Dermato-Venereologica - Category: Dermatology Authors: Tags: Acta Derm Venereol Source Type: research
We report an atypical case of European LCLB, suggesting that ACA is not the only possible presentation of LCLB. The diagnosis of ACA is often clinically missed for months or years, and may be mistaken at the inflammation phase for vascular disorders, erysipelas or bursitis/arthritis, and at the atrophic phase for lichen sclerosus atrophicus, morphoea or anetoderma. To our knowledge, no such tumorous LCLB has previously been described.
Source: British Journal of Dermatology - Category: Dermatology Authors: Tags: Case Report: Clinical and Diagnostic Source Type: research
Authors: Ohn J, Park SY, Moon J, Choe YS, Kim KH Abstract Morgellons disease is a rare disease with unknown etiology. Herein, we report the first case of Morgellons disease in Korea. A 30-year-old woman presented with a 2-month history of pruritic erythematous patches and erosions on the arms, hands, and chin. She insisted that she had fiber-like materials under her skin, which she had observed through a magnifying device. We performed skin biopsy, and observed a fiber extruding from the dermal side of the specimen. Histopathological examination showed only mild lymphocytic infiltration, and failed to reveal eviden...
Source: Annals of Dermatology - Category: Dermatology Tags: Ann Dermatol Source Type: research
by Eva Ru žić-Sabljić, Vera Maraspin, Daša Stupica, Tereza Rojko, Petra Bogovič, Franc Strle, Tjaša Cerar The isolation ofB.burgdorferi sensu lato requires the use of complex cultivation media. The aim of the study was to compare the usefulness of BSK-H (a commercial medium produced by HiMedia, India) and MKP medium. MKP and BSK-H media were prepared in accordance with the relevant protocols.Borrelia strains and skin culture biopsies were simultaneously inoculated into both media, incubated and checked for growth. Borrelial growth characteristics, isolation rates and characteristics of the isolated borre...
Source: PLoS One - Category: Biomedical Science Authors: Source Type: research
Publication date: Available online 30 December 2016 Source:Ticks and Tick-borne Diseases Author(s): Alex Wagemakers, Seta Jahfari, Bob de Wever, Lodewijk Spanjaard, Markus V Starink, Henry JC de Vries, Hein Sprong, Joppe W. Hovius Ixodes ticks transmit Borrelia burgdorferi sensu lato (s.l.), the causative agent of Lyme borreliosis (LB). These tick species also transmit Borrelia miyamotoi, which was recently found to cause infections in humans. We were interested in the prevalence of B. miyamotoi infection in ticks and natural hosts in the Netherlands, and to what extent ticks are co-infected with B. burgdorferi. In additi...
Source: Ticks and Tick borne Diseases - Category: Zoology Source Type: research
aacute; L, Sprong H, Kazimírová M Abstract Borrelia miyamotoi causes relapsing fever in humans. The occurrence of this spirochete has been reported in Ixodes ricinus and wildlife, but there are still gaps in the knowledge of its eco-epidemiology and public health impact. In the current study, questing I. ricinus (nymphs and adults) and skin biopsies from rodents captured in Slovakia were screened for the presence of B. miyamotoi and Borrelia burgdorferi s.l. DNA. The prevalence of B. miyamotoi and B. burgdorferi s.l. in questing ticks was 1.7 and 16.9%, respectively. B. miyamotoi was detected in Apod...
Source: Microbial Ecology - Category: Microbiology Authors: Tags: Microb Ecol Source Type: research
Conclusions. BL is a rare manifestation of early localized LB. Fourteen-day antibiotic treatment, as used for erythema migrans, is effective.
Source: Clinical Infectious Diseases - Category: Infectious Diseases Authors: Tags: ARTICLES AND COMMENTARIES Source Type: research
Publication date: Available online 31 August 2016 Source:Veterinary Immunology and Immunopathology Author(s): Deborah A. Grosenbaugh, Daniel R. Rissi, Paula M. Krimer Lyme disease in dogs can be effectively prevented by vaccination against antigens expressed by the spirochete Borrelia burgdorferi during transmission by the tick vector Ixodes sp. Lyme vaccine efficacy has traditionally been based on indicators of infection following wild-caught tick challenge whereas most other types of vaccine are required to demonstrate protection from clinical signs of disease. In this vaccination-challenge study we sought to demonstrat...
Source: Veterinary Immunology and Immunopathology - Category: Veterinary Research Source Type: research
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