‘Impact of an Additional Chromosome on the Clinical Outcomes of Hematopoietic Stem Cell Transplantation in Philadelphia Chromosome-Positive Acute Myeloid Leukemia in Adults’

• Philadelphia positive AML patients can benefit from TKI interim therapy along with standard chemotherapy to achieve complete remission.• Minimal residual disease negativity could be a predictor of better clinical outcome after allogeneic hematopoietic cell transplantation.• The presence of i nv (16) in patients with Ph-positive AML associated with better survival outcome.

Source: Biology of Blood and Marrow Transplantation - April 23, 2018 Category: Hematology Authors: Gi June MIN, Hee-Je Kim, Jae-Ho Yoon, Dae-hun Kwak, Sung-Soo Park, Young-Woo Jeon, Sung-Eun Lee, Byung-Sik Cho, Ki-Seong Eom, Yoo-Jin Kim, Seok Lee, Chang-Ki Min, Seok-Goo Cho, Dong-Wook Kim, Jong Wook Lee, Woo-Sung Min Source Type: research