FDA Clears First Test for Emerging Pathogen Candida auris FDA Clears First Test for Emerging Pathogen Candida auris

The Bruker Maldi Biotyper CA system can reliably identify C auris 100% of the time.FDA Approvals
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Infectious Diseases News Alert Source Type: news

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Publication date: Available online 19 March 2019Source: IDCasesAuthor(s): Tania Ahuja, Karen Fong, Eddie LouieAbstractAlthough Candida species are common pathogens for nosocomial infections, Candida endocarditis is still considered a rare entity. Here, we report two cases of Candida parapsilosis endovascular infections in patients with prosthetic valves, both of which responded to combination antifungal therapy without surgical intervention. Additionally, T2 magnetic resonance (T2MR) was used to assess for resolution of invasive candidiasis. The first case is of an elderly man with Candida parapsilosis endovascular infecti...
Source: IDCases - Category: Infectious Diseases Source Type: research
Abstract A 47-year-old white woman presented to our clinic complaining of recalcitrant warts on her trunk and extremities. She had an extensive past medical history including immunodeficiency of unknown origin, pulmonary hypertension, rheumatoid arthritis, and systemic lupus erythematosus, for which she was being treated with chronic immunosuppressive therapy with methylprednisolone and belimumab. The patient had previously failed treatments at an outside facility with liquid nitrogen, trichloroacetic acid, topical cidofovir, imiquimod, topical 5-fluorouracil, intralesional candida antigen, pulsed-dye laser (Vbeam...
Source: Skinmed - Category: Dermatology Authors: Tags: Skinmed Source Type: research
Authors: Zhang Q, Li Z, Xu K, Qian Y, Chen M, Sun L, Song S, Huang X, He Z, Li F, Zhang D, Yang L, Wang Y, Xu H, Xu Z Abstract BACKGROUND: We aimed to investigate the role of intracellular imatinib concentration in drug resistance and the expression of candidate drug transporters in gastrointestinal stromal tumor (GIST) cell lines. METHOD: The imatinib concentrations were measured by the liquid chromatography-tandem mass spectrometry (LC-MS/MS). The expression of candida te drug transporters was detected by qRT-PCR. RESULTS: The tissue imatinib concentrations in imatinib resistant patients were significantl...
Source: Scandinavian Journal of Gastroenterology - Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research
Authors: Nakano M, Suzuki M, Wakabayashi H, Hayama K, Yamauchi K, Abe F, Abe S Abstract Candida albicans is a commensal fungus in human mucosal surfaces, including the oral cavity. Lactoferrin (LF) and the lactoperoxidase (LPO) system, which are host protection components in exocrine secretions, each exhibit weak anti-candida activity. We herein examined the effects of the combination of LF and the LPO system on C. albicans. Morphological observations indicated that the combination of LF and the LPO system reduced the mycelial volume of C. albicans and changed the size and shape of cells more than each agent alone....
Source: Drug Discoveries and Therapeutics - Category: Drugs & Pharmacology Tags: Drug Discov Ther Source Type: research
Publication date: Available online 18 March 2019Source: Food ChemistryAuthor(s): N. Arroyo-Manzanares, B. Markiv, J.D. Hernández, I. López-García, I. Guillén, P. Vizcaíno, M. Hernández-Córdoba, P. ViñasAbstractHead-space (HS) gas chromatography (GC) coupled to mass spectrometry (MS) is proposed for the assessment of the contamination of mayonnaise as an alternative to plate counting, which is the technique commonly used for evaluating microbial contamination. More specifically, this method was applied in the detection of Candida metapsilosis and Zygosaccharomyces bail...
Source: Food Chemistry - Category: Food Science Source Type: research
Publication date: Available online 18 March 2019Source: Journal of BiotechnologyAuthor(s): R. Gustavsson, C.F. Mandenius, S. Löfgren, T. Scheper, P. LindnerAbstractMicrobial contamination in mammalian cell cultures causing rejected batches is costly and highly unwanted. Most methods for detecting a contamination are time-consuming and require extensive off-line sampling. To circumvent these efforts and provide a more convenient alternative, we used an online in situ microscope to estimate the cell diameter of the cellular species in the culture to distinguish mammalian cells from microbial cells depending on their siz...
Source: Journal of Biotechnology - Category: Biotechnology Source Type: research
Publication date: Available online 18 March 2019Source: International Journal of PharmaceuticsAuthor(s): Maria I. Cardona, Nguyet-Minh Nguyen Le, Sergey Zaichik, Diana M. Aragón, Andreas Bernkop- SchnürchAbstractThe aim of this study was to develop and evaluate a self-emulsifying delivery system (SEDDS) for oral rutin fatty ester administration and to improve its mucus permeating properties by the incorporation of the silicon polymer poly [dimethylsiloxane-co-(3-(2-(2-hydroxyethoxy)ethoxy)propyl]methylsiloxane] (PDMSHEPMS) in the formulation. In order to increase the lipophilicity of the flavonoid and to dissol...
Source: International Journal of Pharmaceutics - Category: Drugs & Pharmacology Source Type: research
Eugenio Mancera, Corey Frazer, Allison M. Porman, Susana Ruiz-Castro, Alexander D. Johnson, Richard J. Bennett
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
CONCLUSION: Therefore, it can be concluded from this study that SLs derived from fermented palm oil have potent antiangiogenic activity which may be attributed by its oleic acid component.
Source: Indian Journal of Pharmacology - Category: Drugs & Pharmacology Authors: Source Type: research
This article is protected by copyright. All rights reserved.
Source: Biotechnology Progress - Category: Biotechnology Authors: Tags: RESEARCH ARTICLE Source Type: research
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