Blood lipid genetic scores, the HMGCR gene and cancer risk: a Mendelian randomization study

ConclusionsUnder the assumptions of Mendelian randomization, there is a causal and negative association between serum triglycerides and risk of any cancer. Further, theHMGCR genetic variant might be associated with risks of prostate and breast cancers but the biological mechanisms behind these findings are unclear, as the LDLC IV was not associated with these cancers.
Source: International Journal of Epidemiology - Category: Epidemiology Source Type: research