Subclinical device-detected atrial fibrillation and stroke risk: a systematic review and meta-analysis

AbstractAimsTo determine stroke risk in subclinical atrial fibrillation (AF) and temporal association between subclinical AF and stroke.Methods and resultsPubmed/Embase was searched for studies reporting stroke in subclinical AF in patients with cardiac implantable electronic devices (CIEDs). After exclusions, 11 studies were analysed. Of these seven studies reported prevalence of subclinical AF, two studies reported association between subclinical and clinical AF, seven studies reported stroke risk in subclinical AF, and five studies reported temporal relationship between subclinical AF and stroke. Subclinical AF was noted after CIEDs implant in 35% [interquartile range (IQR) 34 –42] of unselected patients with pacing indication over 1–2.5 years. The definition and cut-off duration (for stroke risk) of subclinical AF varied across studies. Subclinical AF was strongly associated with clinical AF (OR 5.7, 95% CI 4.0–8.0,P   defined cut-off duration was 1.89/100 person-year (95% CI 1.02–3.52) with 2.4-fold (95% CI 1.8–3.3,P 
Source: European Heart Journal - Category: Cardiology Source Type: research

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Source: The American Journal of Medicine - Category: General Medicine Authors: Source Type: research
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Source: Journal of Interventional Cardiac Electrophysiology - Category: Cardiology Source Type: research
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Source: Journal of General Internal Medicine - Category: Internal Medicine Source Type: research
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Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
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Source: Brain and Behavior - Category: Neurology Authors: Tags: ORIGINAL RESEARCH Source Type: research
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Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research
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