Pharmacodynamics of inhaled amikacin (BAY 41-6551) studied in an in vitro pharmacokinetic model of infection

ConclusionsAnfAUC/MIC amikacin target of 50 –80 is appropriate for aerobic Gram-negative bacilli and mean ELF concentrations of BAY 41-6551 would produce a static to −1 log clearance with strains up to 128 mg/L.
Source: Journal of Antimicrobial Chemotherapy - Category: Microbiology Source Type: research