Avoid piperacillin-tazobactam when treating BSI cause by ceftriaxone-resistant pathogens
(European Society of Clinical Microbiology and Infectious Diseases) The antibiotic combination treatment piperacillin-tazobactam was significantly less effective than meropenem when treating potentially fatal bloodstream infections (BSI) caused by ceftriaxone-resistant Escherichia coli and Klebsiella pneumoniae and should be avoided when treating these organisms, according to research presented at the 28th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID).
Chem. Commun., 2021, Advance Article DOI: 10.1039/D1CC04401J, CommunicationTatsuki Deyama, Yukino Matsui, Yuhei Chadani, Yasuhiko Sekine, Nobuhide Doi, Kei Fujiwara Here we created artificial cells in which information of the genome of living cells is expressed by the elements encoded in the genome. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
CONCLUSION: Curcumin was thought to be an alternative antimicrobial in combination therapies that would positively contribute to the treatment of bacterial infection. The effectiveness of this combination should be confirmed by other in vitro and clinical studies.PMID:34540173 | PMC:PMC8416589 | DOI:10.18502/ijm.v13i3.6397
CONCLUSION: Management of women with UTI caused by the CIPR/ESBL+ isolates (ST131) co-harbored PMQR, ESBL, and chromosomal mutations, is important for their effective therapy.PMID:34540167 | PMC:PMC8416580 | DOI:10.18502/ijm.v13i3.6389
CONCLUSION: There is a paucity of literature on anaerobe isolation from surgical infections from our country which motivated us to study anaerobic infections and the high sample size in our institute enabled us to study surgical infections from an anaerobic perspective. This will add to the knowledge of microbiologists and clinicians. MALDI-TOF MS helped in rapid and accurate identification and hence we could report a wider spectrum of organisms in our study.PMID:34540165 | PMC:PMC8416598 | DOI:10.18502/ijm.v13i3.6387
CONCLUSION: The findings obtained in the work showed that A. negrei can serve as a valuable source of natural compounds that can be used as a new weapon to fight radical damage and resistant microbes.PMID:34539801 | PMC:PMC8443344 | DOI:10.1155/2021/5902851
CONCLUSION: The results of the present work show that the raised antibody against recombinant AcAMP can be used to detect AcAMP peptide, an issue which paves the way to develop detection kits for the detection of AcAMP-producing organisms, purification of this valuable peptide for further investigations.PMID:34540159 | PMC:PMC8408025 | DOI:10.18502/ijm.v13i2.5985
CONCLUSION: The study revealed an alarming rate of resistance to the commonly used antimicrobial agents used in treating HAIs. Also the relationship between AMR and some risk factors and thus taking steps towards controlling them have been shown.PMID:34540152 | PMC:PMC8408023 | DOI:10.18502/ijm.v13i2.5978
Iran J Microbiol. 2021 Apr;13(2):156-160. doi: 10.18502/ijm.v13i2.5974.ABSTRACTBACKGROUND AND OBJECTIVES: Escherichia coli is a Gram-negative organism causing mild to severe infections, with a wide spectrum range of organs involved. The study aimed to describe antibiotics susceptibility of E. coli from clinical specimens from October 11, 2019 to September 11, 2020.MATERIALS AND METHODS: Study was conducted retrospectively in a private microbiology laboratory in Mataram Indonesia. Period of study divided as two groups after WHO declared COVID-19 as pandemic by March 11, 2020; group A including the specimen related to Septem...
CONCLUSION: The genetic variation of recombinant CYP3A4 affects the MBI profile of CYP3A4 by erythromycin and clarithromycin, while the influence of genetic variation was similarly observed regardless of substrates. Our findings are of clinical relevance because the residual enzyme activity of CYP3A4 in the presence of inhibitor was estimated to vary among genetic variants.PMID:34542401 | DOI:10.5414/CP203896
This study is aimed at elucidating the mechanism of action of the antibacterial effect of these plants on some bacterial strains responsible for diarrheal infections. The design of the study included first evaluating the degree of sensitivity of Salmonella typhimurium 14028, Escherichia coli ATCC 25922, Shigella spp., and Salmonella spp. strains to aqueous and hydroethanolic extracts of each plant, followed by the determination of minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and antibiotic power (Pa). This screening was completed with the evaluation of the possible mode of action of the...