AIDS-related malignant disease

Immunodeficiency, whether congenital or acquired, iatrogenic (e.g. allograft recipients) or infectious (e.g. human immunodeficiency virus (HIV)), is associated with an increased risk of malignancy. In the case of HIV infection, most cancers are associated with oncogenic virus infection. Although the overall risk of any cancer is increased 2 –3-fold in people living with HIV, there are three acquired immune deficiency syndrome (AIDS)-defining cancers whose relative risk is dramatically higher. These three AIDS-defining illnesses are Kaposi's sarcoma, high-grade B cell non-Hodgkin's lymphoma (including primary cerebral lymphoma) and in vasive cervical cancer.

Source: Medicine - April 21, 2018 Category: Internal Medicine Authors: Alessia Dalla Pria, Mark Bower Tags: HIV and its complications Source Type: research