Brachytherapy for cervical cancer does not increase the risk of ureteral stricture
(European Society for Radiotherapy and Oncology (ESTRO)) New research presented at the ESTRO 37 conference from two large international trials, shows that intracavitary and interstitial brachytherapy is safe and does not increase the risk of ureteral stricture in cervical cancer patients. Until now, there have been concerns that brachytherapy might increase the risk of this serious, sometimes life-threatening complication, although the treatment itself is associated with better survival.
Publication date: Available online 7 May 2019Source: Journal of Minimally Invasive GynecologyAuthor(s): Dan Zhao, Bin Li, Yating Wang, Shuanghuan Liu, Yanan Zhang, Guangwen YuanABSTRACTStudy ObjectiveTo explore the feasibility of nerve plane–sparing laparoscopic radical hysterectomy (NPS-LRH) as a simplified C1-type surgery for cervical cancer patients and to compare this technique with laparoscopic radical hysterectomy (LRH).DesignA retrospective comparative study.SettingAn academic tertiary hospital affiliated with the Chinese National Cancer Center.PatientsSix hundred fifteen patients with Fédération...
Publication date: Available online 7 May 2019Source: Journal of Minimally Invasive GynecologyAuthor(s): Dan Zhao, Bin Li, Yating Wang, Shuanghuan Liu, Yanan Zhang, Guangwen YuanAbstractStudy ObjectivesTo explore the feasibility of nerve plane-sparing laparoscopic radical hysterectomy (NPS-LRH) as a simplified C1 type surgery for cervical cancer patients, and to compare this technique with laparoscopic radical hysterectomy (LRH).DesignA retrospective comparative studySettingAn academic tertiary hospital affiliated with the Chinese national cancer center.Patients615 patients with FIGO stage Ib and IIa cervical cancer who und...
The use of image-guided 3D conformal brachytherapy for cervical cancer has led to improved tumor local control as a Result of the ability to dose-escalate. However, some critical organs, like the ureters, are hard to visualize in modern imaging, and these structures may be at risk of severe complications. Hence, we sought to report the rate of late grade ≥3 ureteral stenosis after 3D MRI-based brachytherapy for cervical cancer.
Publication date: Available online 24 April 2019Source: Gynecologic Oncology ReportsAuthor(s): Brooke Liang, Sara S. Lange, L. Stewart Massad, Rebecca Dick, Kathryn A. Mills, Andrea R. Hagemann, Carolyn K. McCourt, Premal H. Thaker, Katherine C. Fuh, David G. Mutch, Matthew A. Powell, Lindsay M. KurokiAbstractObjectiveTo assess the renal outcomes of gynecologic oncology patients who present with hydronephrosis and acute kidney injury (AKI), have
CONCLUSION: Fluoroscopic guided percutaneous ureteral stents placement is a safe, efficient procedure and has a high success rate in patients with malignant ureteral obstruction. PMID: 30909269 [PubMed - as supplied by publisher]
Conclusions: The LENT SOMA system was acceptable and feasible to use and gave us an insight into the morbidity in our patients and to develop effective management plans to reduce the post treatment symptoms and improve quality of life. PMID: 30803196 [PubMed - in process]
ConclusionsWe found the precise anatomy of the connective tissue layer from umbilical artery to urinary bladder and the superior vesical artery. Our procedure based on the precise anatomy obtained in this study is reasonable anatomically as a method for separation of the vesicouterine ligament during radical hysterectomy.
Hydronephrosis is a sign of advanced stage disease in patients with cervical cancer. Its presence is believed to negatively affect the survival of patients. To date, however, consensus in this field is still lacking. The purpose of the present systematic review is to gather the available data and to provide directions for future research in the field. We systematically searched Medline, Scopus, Clinicaltrials.gov, EMBASE, Cochrane Central Register of Controlled Trials CENTRA and Google Scholar databases from inception till June 2018. Overall, 22 studies were included in the present systematic review that evaluated outcomes...
This report describes the incidence and risk factors for ureteral stricture in a large patient cohort treated with 3-dimensional image guided adaptive brachytherapy and radiochemotherapy within the EMBRACE studies.
This study describes the incidence and predictive factors for grade 3-4 ureteral stricture in 1860 patients treated for locally advanced cervical cancer (LACC) with 3D image guided adaptive brachytherapy (IGABT) and radiochemotherapy. Severe to life threatening ureteral stricture occurs rarely in LACC patients with T1-2 tumors (5-year risk ≤ 1%). Advanced tumor stage T3-4 with hydronephrosis at diagnosis was the only independent risk factors, resulting in a 5-year risk of 11.5% for ureteral stricture.